2016
Novel anatomic adaptation of cortical bone to meet increased mineral demands of reproduction
Macica CM, King HE, Wang M, McEachon CL, Skinner CW, Tommasini SM. Novel anatomic adaptation of cortical bone to meet increased mineral demands of reproduction. Bone 2016, 85: 59-69. PMID: 26825813, PMCID: PMC7429445, DOI: 10.1016/j.bone.2015.12.056.Peer-Reviewed Original ResearchConceptsHyp miceMineral homeostasisElevated serum PTHMaternal bone massMineralized trabecular boneIntestinal calcium absorptionCortical boneWild-type miceSerum PTHCalcitriol productionFemale patientsMaternal skeletonPostnatal nutritionCalcium absorptionBone resorptionFracture riskMaternal adaptationBone massBone fragilityMurine modelIntracortical porosityUnaffected miceMouse modelMMP-13Fetal development
2008
Biological Co‐Adaptation of Morphological and Composition Traits Contributes to Mechanical Functionality and Skeletal Fragility1*
Tommasini SM, Nasser P, Hu B, Jepsen KJ. Biological Co‐Adaptation of Morphological and Composition Traits Contributes to Mechanical Functionality and Skeletal Fragility1*. Journal Of Bone And Mineral Research 2008, 23: 236-246. PMID: 17922614, PMCID: PMC2665697, DOI: 10.1359/jbmr.071014.Peer-Reviewed Original Research