2023
Lead induced differences in bone properties in osteocalcin +/+ and −/− female mice
Yildirim G, Budell W, Berezovska O, Yagerman S, Maliath S, Mastrokostas P, Tommasini S, Dowd T. Lead induced differences in bone properties in osteocalcin +/+ and −/− female mice. Bone Reports 2023, 18: 101672. PMID: 37064000, PMCID: PMC10090701, DOI: 10.1016/j.bonr.2023.101672.Peer-Reviewed Original ResearchBone strengthMineral/matrixBone remodelingHigher blood lead levelsSerum turnover markersLow lead exposureMajor health problemBlood lead levelsRole of osteocalcinBV/TVBone mineral propertiesTurnover markersFracture riskFemale miceLead exposureHealth problemsEffects of leadLead levelsBone formationCollagen maturityCross-sectional areaOsteocalcinLead toxicityBone propertiesBiomechanical measurements
2018
Human Amniotic Membrane Improves Healing in a Chronic, Massive Rotator Cuff Repair Model
Kovacevic D, Suriani R, Saad M, Tommasini S, Mendias C, Carroll C, Blaine T. Human Amniotic Membrane Improves Healing in a Chronic, Massive Rotator Cuff Repair Model. Orthopaedic Journal Of Sports Medicine 2018, 6: 2325967118s00167. PMCID: PMC6102762, DOI: 10.1177/2325967118s00167.Peer-Reviewed Original ResearchTendon-bone interfaceRotator cuff injuryHuman amniotic membraneER groupAmniotic membraneCuff injuryChronic injuryLipid depositionCross-sectional areaMuscle fiber forcePAI-1Male Sprague-Dawley ratsRepair gene expressionBone formationPlasminogen activator inhibitor-1 expressionRotator cuff tendon–bone healingTransosseous suture fixationRepair siteRotator cuff repair modelMuscle fibersTendon-bone healingSprague-Dawley ratsRotator cuff musclesLess PAI-1Real-time polymerase chain reaction
2014
Periosteal PTHrP regulates cortical bone modeling during linear growth in mice
Wang M, VanHouten JN, Nasiri AR, Tommasini SM, Broadus AE. Periosteal PTHrP regulates cortical bone modeling during linear growth in mice. Journal Of Anatomy 2014, 225: 71-82. PMID: 24762197, PMCID: PMC4073294, DOI: 10.1111/joa.12184.Peer-Reviewed Original ResearchConceptsMetaphyseal-diaphyseal junctionParathyroid hormone-related peptideEndocortical bone formationCD-1 miceNF-kB ligandHormone-related peptideMineral apposition rateCortical bone modelingEntire boneLinear growthAnteromedial cortexCKO miceProximal tibiaLateral tibiaReceptor activatorOC numberApposition rateOsteoclastic resorptionPTHrPBone modelingBone formationFibulaLong bonesMicePeriosteum