2008
Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains
Jepsen KJ, Hu B, Tommasini SM, Courtland HW, Price C, Cordova M, Nadeau JH. Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains. Mammalian Genome 2008, 20: 21. PMID: 19082857, PMCID: PMC2650248, DOI: 10.1007/s00335-008-9158-1.Peer-Reviewed Original ResearchConceptsGenetic variantsSkeletal traitsFunctional interactionMatrix mineralizationCompensatory interactionsGenotype-phenotype relationshipsPhenotypic integrationAdult traitsLoss of functionBiological controlPrecise regulationMouse strainsAXB/BXASusceptibility genesInner bone surfaceTraitsEnvironmental variantsPostnatal growthNew insightsBone slendernessQuantitative expectationsVariantsGrowthSkeletal growthExpansion rate
2007
Path analysis using data derived from genetically randomized inbred mouse strains reveals biological controls affecting bone growth and adult fragility
Jepsen K, Hu B, Tommasini S, Courtland H, Price C, Terranova C, Nadeau J. Path analysis using data derived from genetically randomized inbred mouse strains reveals biological controls affecting bone growth and adult fragility. Bone 2007, 40: s53. DOI: 10.1016/j.bone.2007.04.064.Peer-Reviewed Original ResearchBiological controlMouse strains