2015
Role of Multiple-Scale Modeling of Epilepsy in Seizure Forecasting
Kuhlmann L, Grayden D, Wendling F, Schiff S. Role of Multiple-Scale Modeling of Epilepsy in Seizure Forecasting. Journal Of Clinical Neurophysiology 2015, 32: 220-226. PMID: 26035674, PMCID: PMC4455036, DOI: 10.1097/wnp.0000000000000149.Peer-Reviewed Original Research
2012
Seizures as imbalanced up states: excitatory and inhibitory conductances during seizure-like events
Žiburkus J, Cressman J, Schiff S. Seizures as imbalanced up states: excitatory and inhibitory conductances during seizure-like events. Journal Of Neurophysiology 2012, 109: 1296-1306. PMID: 23221405, PMCID: PMC3602838, DOI: 10.1152/jn.00232.2012.Peer-Reviewed Original ResearchConceptsSeizure-like eventsO-LM cellsPyramidal cellsInhibitory conductanceOriens-lacunosum moleculare (O-LM) interneuronsNeuronal network hyperexcitabilityExcitability of interneuronsCA1 pyramidal cellsInhibitory synaptic conductancesNetwork hyperexcitabilityRecurrent seizuresMoleculare interneuronsSeizure initiationNeural network activityRat hippocampusExtracellular magnesiumSynaptic barragesFiring patternsSeizuresExcitatoryCellular subtypesSynaptic conductancesInterneuronsNetwork activityCell typesModulation of hippocampal rhythms by subthreshold electric fields and network topology
Berzhanskaya J, Chernyy N, Gluckman B, Schiff S, Ascoli G. Modulation of hippocampal rhythms by subthreshold electric fields and network topology. Journal Of Computational Neuroscience 2012, 34: 369-389. PMID: 23053863, PMCID: PMC3549326, DOI: 10.1007/s10827-012-0426-4.Peer-Reviewed Original ResearchConceptsPyramidal cellsGamma rhythmsHippocampal rhythmsSubthreshold electric fieldsSpecific synaptic connectivityExact cellular mechanismsExcitatory contactsSynaptic circuitryBasket cellsLines of resultsArea CA1Inhibitory connectivityInterneuron typesSynaptic connectivityInterneuron classesHippocampal functionNeuron typesNeuronal morphologyTheta/gamma ratioCognitive functionTheta frequencyCellular mechanismsNeural activityElectrophysiological dataNovel role
2010
Towards model-based control of Parkinson's disease
Schiff S. Towards model-based control of Parkinson's disease. Philosophical Transactions Of The Royal Society A Mathematical Physical And Engineering Sciences 2010, 368: 2269-2308. PMID: 20368246, PMCID: PMC2944387, DOI: 10.1098/rsta.2010.0050.Peer-Reviewed Original Research
2006
Interneuron and Pyramidal Cell Interplay During In Vitro Seizure-Like Events
Ziburkus J, Cressman J, Barreto E, Schiff S. Interneuron and Pyramidal Cell Interplay During In Vitro Seizure-Like Events. Journal Of Neurophysiology 2006, 95: 3948-3954. PMID: 16554499, PMCID: PMC1469233, DOI: 10.1152/jn.01378.2005.Peer-Reviewed Original Research
2004
Analytical coupling detection in the presence of noise and nonlinearity
Netoff T, Pecora L, Schiff S. Analytical coupling detection in the presence of noise and nonlinearity. Physical Review E 2004, 69: 017201. PMID: 14995756, DOI: 10.1103/physreve.69.017201.Peer-Reviewed Original Research
2003
Sensitivity of Neurons to Weak Electric Fields
Francis J, Gluckman B, Schiff S. Sensitivity of Neurons to Weak Electric Fields. Journal Of Neuroscience 2003, 23: 7255-7261. PMID: 12917358, PMCID: PMC6740448, DOI: 10.1523/jneurosci.23-19-07255.2003.Peer-Reviewed Original Research
2002
Decreased Neuronal Synchronization during Experimental Seizures
Netoff T, Schiff S. Decreased Neuronal Synchronization during Experimental Seizures. Journal Of Neuroscience 2002, 22: 7297-7307. PMID: 12177225, PMCID: PMC6757884, DOI: 10.1523/jneurosci.22-16-07297.2002.Peer-Reviewed Original Research
2001
Adaptive Electric Field Control of Epileptic Seizures
Gluckman B, Nguyen H, Weinstein S, Schiff S. Adaptive Electric Field Control of Epileptic Seizures. Journal Of Neuroscience 2001, 21: 590-600. PMID: 11160438, PMCID: PMC6763796, DOI: 10.1523/jneurosci.21-02-00590.2001.Peer-Reviewed Original Research
1994
Controlling chaos in the brain
Schiff S, Jerger K, Duong D, Chang T, Spano M, Ditto W. Controlling chaos in the brain. Nature 1994, 370: 615-620. PMID: 8065447, DOI: 10.1038/370615a0.Peer-Reviewed Original Research