2005
Analysis and Design of Turns in α-Helical Hairpins
Lahr S, Engel D, Stayrook S, Maglio O, North B, Geremia S, Lombardi A, DeGrado W. Analysis and Design of Turns in α-Helical Hairpins. Journal Of Molecular Biology 2005, 346: 1441-1454. PMID: 15713492, DOI: 10.1016/j.jmb.2004.12.016.Peer-Reviewed Original Research
2003
X-ray Structure of a Maquette Scaffold
Huang S, Gibney B, Stayrook S, Dutton P, Lewis M. X-ray Structure of a Maquette Scaffold. Journal Of Molecular Biology 2003, 326: 1219-1225. PMID: 12589764, DOI: 10.1016/s0022-2836(02)01441-9.Peer-Reviewed Original ResearchConceptsLeft-handed coiled-coilsCoiled-coilAnti-parallel four-helix bundleHeptad repeat patternFour-alpha-helical bundleMaquette scaffoldFour-helix bundleHeme-binding propertiesX-ray structureMAD phasingHeme binding pocketIdentical helicesResidue positionsHeptad repeatHydrophobic residuesPacking interfaceProtein scaffoldEngineering criteriaHeptadMaquettesRepeat patternHelixDesign criteriaX-rayInitial design