1987
Changes in synaptic morphology associated with presynaptic and postsynaptic activity: An in vitro study of the electrosensory organ of the thornback ray
Fields R, Ellisman M, Waxman S. Changes in synaptic morphology associated with presynaptic and postsynaptic activity: An in vitro study of the electrosensory organ of the thornback ray. Synapse 1987, 1: 335-346. PMID: 2901790, DOI: 10.1002/syn.890010407.Peer-Reviewed Original ResearchConceptsPostsynaptic membraneNeurotransmitter glutamateSynaptic morphologyUltrastructure of synapsesPresynaptic membraneRibbon synapsesDirect depolarizationSynaptic activityPostsynaptic activitySpontaneous activitySynaptic fatigueSynaptic efficacyMorphological changesSynaptic structureSynapsesCytoskeletal alterations
1985
Retrograde labeling of regenerated electromotor neurons with HRP in a teleost fish, Sternarchus albifrons: Relation to cell death
Anderson M, Fong H, Waxman S. Retrograde labeling of regenerated electromotor neurons with HRP in a teleost fish, Sternarchus albifrons: Relation to cell death. Cell And Tissue Research 1985, 241: 237-240. PMID: 2411410, DOI: 10.1007/bf00217166.Peer-Reviewed Original ResearchConceptsCorrect target areaElectromotor neuronsRetrograde labelingCell deathSelective neuronal deathSternarchus albifronsSubsequent cell deathNeuronal deathSpinal cordAxonal projectionsEctopic neuronsSelective cell deathTeleost fishImplantation sitesEctopic cellsNeuronsAxonsDeathCordAlbifronsTarget areaHorseradish peroxidase
1984
Cell death of asynaptic neurons in regenerating spinal cord
Anderson M, Waxman S, Tadlock C. Cell death of asynaptic neurons in regenerating spinal cord. Developmental Biology 1984, 103: 443-455. PMID: 6724138, DOI: 10.1016/0012-1606(84)90332-4.Peer-Reviewed Original ResearchConceptsSpinal cordElectromotor neuronsRegenerated cordNormal numbersNumber of perikaryaCell deathCaudal endRostro-caudal axisSpinal neuronsCordCell bodiesNeuronsSynaptic competitionAxonsNumerous cellsDeathPerikaryaAmputationMore yearsEvidence of migrationSternarchus albifronsExcess numberElectric organEpendymaTransverse sections
1983
Regeneration of spinal neurons in inframammalian vertebrates: morphological and developmental aspects.
Anderson M, Waxman S. Regeneration of spinal neurons in inframammalian vertebrates: morphological and developmental aspects. Journal Für Hirnforschung 1983, 24: 371-98. PMID: 6643991.Peer-Reviewed Original ResearchConceptsSpinal cordNerve cell bodiesSpinal neuronsCell bodiesNerve fibersAxon reactionElectromotor neuronsInframammalian vertebratesSpinal electromotor neuronsPeripheral nerve bridgesMammalian spinal cordCell deathNerve bridgeNew neuronsEpendymal cellsTrophic effectsCordNerve growthNeuronsNerve outgrowthCertain hormonesGrowth factorSternarchusExternal laminaAxon outgrowth
1980
Coordinated micropinocytotic activity of adjacent neuronal membranes in mammalian central nervous system
Waxman S, Waxman M, Pappas G. Coordinated micropinocytotic activity of adjacent neuronal membranes in mammalian central nervous system. Neuroscience Letters 1980, 20: 141-146. PMID: 7443064, DOI: 10.1016/0304-3940(80)90136-6.Peer-Reviewed Original ResearchConceptsExocytosis/endocytosisMembrane infoldingsMammalian central nervous systemCoated invaginationsNon-synaptic sitesNeuronal membranesCell membraneCentral nervous systemCoordinated activityNervous systemMembraneInvaginationMicropinocytotic activityInfoldingsElectrotonic synapsesEndocytosisSpeciesCytoplasmTissueNumber of sitesSitesSynapsesWide varietyActivityNeighboring dendritesRegeneration of spinal electrocyte fibers in Sternarchus albifrons: Development of axon-schwann cell relationships and nodes of Ranvier
Waxman S, Anderson M. Regeneration of spinal electrocyte fibers in Sternarchus albifrons: Development of axon-schwann cell relationships and nodes of Ranvier. Cell And Tissue Research 1980, 208: 343-352. PMID: 7397760, DOI: 10.1007/bf00233869.Peer-Reviewed Original Research
1978
Demyelination of Sternarchus electrocyte fibers by injection of diphtheria toxin
Quick D, Waxman S. Demyelination of Sternarchus electrocyte fibers by injection of diphtheria toxin. Journal Of The Neurological Sciences 1978, 35: 235-241. PMID: 632832, DOI: 10.1016/0022-510x(78)90006-0.Peer-Reviewed Original Research
1977
Specific staining of the axon membrane at nodes of Ranvier with ferric ion and ferrocyanide
Quick D, Waxman S. Specific staining of the axon membrane at nodes of Ranvier with ferric ion and ferrocyanide. Journal Of The Neurological Sciences 1977, 31: 1-11. PMID: 64593, DOI: 10.1016/0022-510x(77)90002-8.Peer-Reviewed Original Research
1975
Morphology of spinal electromotor neurons and presynaptic coupling in the gymnotidSternarchus albifrons
Pappas G, Waxman S, Bennett M. Morphology of spinal electromotor neurons and presynaptic coupling in the gymnotidSternarchus albifrons. Brain Cell Biology 1975, 4: 469-478. PMID: 1151441, DOI: 10.1007/bf01261376.Peer-Reviewed Original ResearchConceptsSpinal electromotor neuronsElectromotor neuronsCell bodiesGap junctionsAxosomatic synapsesSpinal cordPresynaptic fibersGlial lamellaeAdjacent neuronsElectrotonic couplingSingle axonsMyelin segmentsNeuronsMedial regionMorphological correlatesMorphological dataElectric organ dischargeAbsence of dendritesAxonsSynapsesAdjacent cellsAlbifronsDendritesLarge majorityCord
1973
Features associated with paranodal demyelination at a specialized site in the non-pathological nervous system
Waxman S. Features associated with paranodal demyelination at a specialized site in the non-pathological nervous system. Journal Of The Neurological Sciences 1973, 19: 357-362. PMID: 4716850, DOI: 10.1016/0022-510x(73)90099-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDemyelinating DiseasesElectric OrganFishesMicroscopy, ElectronMyelin SheathRanvier's NodesSchwann Cells
1972
Regional differentiation of the axon: A review with special reference to the concept of the multiplex neuron
Waxman S. Regional differentiation of the axon: A review with special reference to the concept of the multiplex neuron. Brain Research 1972, 47: 269-288. PMID: 4345196, DOI: 10.1016/0006-8993(72)90639-7.Peer-Reviewed Original ResearchMORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS
Waxman S, Pappas G, Bennett M. MORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS. Journal Of Cell Biology 1972, 53: 210-224. PMID: 5013596, PMCID: PMC2108696, DOI: 10.1083/jcb.53.1.210.Peer-Reviewed Original ResearchConceptsNodes of RanvierTypical nodeMorphological correlatesSurface areaMicroSingle nerve fibersElectron microscopyLarge nodesPacked layerSeries capacitySpinal neuronsTypical structureNerve fibersElectric organLevel of entrySingle fiberMembrane surface areaNeural originRunning segmentsAxonsNodal morphologyFiber axisFibersTypical appearanceUnique neural systems
1971
An ultrastructural study of the pattern of myelination of preterminal fibers in teleost oculomotor nuclei, electromotor nuclei, and spinal cord
Waxman S. An ultrastructural study of the pattern of myelination of preterminal fibers in teleost oculomotor nuclei, electromotor nuclei, and spinal cord. Brain Research 1971, 27: 189-201. PMID: 5552167, DOI: 10.1016/0006-8993(71)90248-4.Peer-Reviewed Original ResearchConceptsPattern of myelinationSpinal cordOculomotor nucleusElectromotor nucleusProportion of synapsesPreterminal fibersPeripheral nerve fibersCentral nervous systemCentral myelinated fibersNodes of RanvierUnmyelinated regionsNerve fibersMyelinated fibersConduction velocityNervous systemCordMyelinationNervous impulsesUltrastructural studySynapsesClose membrane appositionBulbous protrusionsMembrane appositionAxonsNucleus