1999
Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons
Fjell J, Cummins T, Dib-Hajj S, Fried K, Black J, Waxman S. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. Brain Research 1999, 67: 267-282. PMID: 10216225, DOI: 10.1016/s0169-328x(99)00070-4.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnimalsAxotomyCell SizeCell SurvivalDown-RegulationDrug ResistanceFemaleGanglia, SpinalGene ExpressionGlial Cell Line-Derived Neurotrophic FactorLectinsMembrane PotentialsNAV1.8 Voltage-Gated Sodium ChannelNAV1.9 Voltage-Gated Sodium ChannelNerve Growth FactorsNerve Tissue ProteinsNeurons, AfferentNeuropeptidesPatch-Clamp TechniquesRatsRats, Sprague-DawleyRNA, MessengerSciatic NerveSodium ChannelsTetrodotoxinUp-RegulationConceptsTTX-R sodium currentsSNS/PN3Small DRG neuronsTTX-R currentsDRG neuronsIB4- neuronsSodium currentElectrophysiological propertiesSmall dorsal root ganglion neuronsDorsal root ganglion neuronsAxotomized DRG neuronsTTX-S currentsWhole-cell patch-clamp studiesTTX-resistant sodium channelsSciatic nerve transectionAdult DRG neuronsDifferent electrophysiological propertiesNear-normal levelsPatch-clamp studiesNerve transectionGDNF treatmentNeurotrophins NGFGanglion neuronsIsolectin IB4Exogenous NGF
1986
A quantitative study of developing axons and glia following altered gliogenesis in rat optic nerve
Black J, Waxman S, Ransom B, Feliciano M. A quantitative study of developing axons and glia following altered gliogenesis in rat optic nerve. Brain Research 1986, 380: 122-135. PMID: 2428420, DOI: 10.1016/0006-8993(86)91436-8.Peer-Reviewed Original ResearchConceptsRat optic nerveOptic nerve volumeNormal optic nervesOptic nerveNerve volumeTotal glial cellsNerve cross sectionsGlial cellsMyelinated fibersAxonal diameterAge-matched control tissueNeonatal rat optic nerveOptic nerve cross sectionsConcomitant marked reductionProgenitor cellsNumber of oligodendrogliaAge-matched controlsGlial cell developmentDays of ageEnsheathed axonsSystemic injectionNerveAstrocytic lineageControl tissuesGlia
1977
Recapitulation of normal neuro-glial relations in dissociated cell cultures of dorsal root ganglia
Waxman S, Dichter M, Hartwieg E, Matheson J. Recapitulation of normal neuro-glial relations in dissociated cell cultures of dorsal root ganglia. Brain Research 1977, 122: 344-350. PMID: 837233, DOI: 10.1016/0006-8993(77)90300-6.Peer-Reviewed Original Research