1995
An orphan nuclear receptor, mROR α, and its spatial expression in adult mouse brain
Matsui T, Sashihara S, Oh Y, Waxman S. An orphan nuclear receptor, mROR α, and its spatial expression in adult mouse brain. Brain Research 1995, 33: 217-226. PMID: 8750880, DOI: 10.1016/0169-328x(95)00126-d.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBinding SitesBlotting, NorthernBrainCell DifferentiationCell LineGene ExpressionHumansIn Situ HybridizationMiceMolecular Sequence DataNeuronsNuclear Receptor Subfamily 1, Group F, Member 1Olfactory BulbOrgan SpecificityReceptors, Cytoplasmic and NuclearReceptors, Retinoic AcidSequence Homology, Amino AcidThalamusTrans-ActivatorsTransfectionTumor Cells, CulturedConceptsResponsive elementActivation of transcriptionThyroid hormone responsive elementRetinoic acid responsive elementNeural cell lineagesAcid-responsive elementLaminin B1 geneOrphan nuclear receptorHormone-responsive elementsRAR beta geneSitu hybridization analysisRetinoic acid receptor-related orphan receptorTranscription factorsAdult mouse brainCotransfection experimentsP19 cellsCell lineagesReceptor-related orphan receptorNorthern hybridizationAcid receptor-related orphan receptorHybridization analysisSpatial expressionOrphan receptorBeta geneNuclear receptors
1994
Intracellular calcium mobilization and neurite outgrowth in mammalian neurons
Kocsis J, Rand M, Lankford K, Waxman S. Intracellular calcium mobilization and neurite outgrowth in mammalian neurons. Developmental Neurobiology 1994, 25: 252-264. PMID: 8195789, DOI: 10.1002/neu.480250306.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsCaffeineCalciumCalcium ChannelsCell CompartmentationCell DifferentiationCells, CulturedFemaleGanglia, SpinalGene Expression RegulationImage Processing, Computer-AssistedIntracellular FluidIon Channel GatingLasersMicroscopy, FluorescenceModels, BiologicalNeuritesNeuronsRatsRats, WistarTerpenesThapsigarginConceptsDepolarization-induced Ca2Calcium-induced calcium releaseDRG neuronsIntracellular Ca2Cultured adult rat dorsal root ganglion neuronsAdult rat dorsal root ganglion neuronsRat dorsal root ganglion neuronsNeurite outgrowthDorsal root ganglion neuronsIntact intracellular Ca2Intracellular calcium mobilizationIndicator dye fluo-3Nuclear Ca2Dye Fluo-3Endoplasmic reticulum Ca2Ganglion neuronsCalcium mobilizationDependent kinase IICalcium releaseFluo-3NeuronsMammalian neuronsReticulum Ca2Elevated Ca2Elicit neurite outgrowth
1987
Molecular differentiation of neurons from ependyma-derived cells in tissue cultures of regenerating teleost spinal cord
Anderson M, Waxman S, Lee Y, Eng L. Molecular differentiation of neurons from ependyma-derived cells in tissue cultures of regenerating teleost spinal cord. Brain Research 1987, 2: 131-136. PMID: 3113659, DOI: 10.1016/0169-328x(87)90006-4.Peer-Reviewed Original ResearchConceptsTeleost spinal cordSpinal cordCell somataNon-phosphorylated neurofilament proteinMolecular differentiationAnti-neurofilament antibodiesRegenerated cordSMI-32Ependymal cellsRostral areasCordNeurofilament proteinDifferentiated neuronsNeuronal morphologyMonoclonal antibodiesNeuronsEpendymal tubeSomaAntibodiesCellsSeries of culturesMolecular architectureTissue culture
1986
Selforganization of ependyma in regenerating teleost spinal cord: evidence from serial section reconstructions
Anderson M, Choy C, Waxman S. Selforganization of ependyma in regenerating teleost spinal cord: evidence from serial section reconstructions. J Embryol Exp Morph 1986, 96: 1-18. PMID: 3805978, DOI: 10.1242/dev.96.1.1.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell MovementEpendymaFishesMicroscopy, ElectronRegenerationSpinal Cord
1985
Neurogenesis in Adult Vertebrate Spinal Cord in Situ and in Vitro: A New Model Systema
ANDERSON M, WAXMAN S. Neurogenesis in Adult Vertebrate Spinal Cord in Situ and in Vitro: A New Model Systema. Annals Of The New York Academy Of Sciences 1985, 457: 213-233. PMID: 3913365, DOI: 10.1111/j.1749-6632.1985.tb20807.x.Peer-Reviewed Original ResearchConceptsSpinal cordEpendymal cellsNeuron-specific monoclonal antibodiesSpinal cord tissueSternarchus albifronsStudy of neurogenesisFunctional recoveryNew neuronsCord tissuePositive stainingRecent studiesCultured neuronsCordInjuryNeurogenesisMonoclonal antibodiesNeuronal differentiationNormal morphologic structureCNSExplant culturesNeuronsVertebrate spinal cordSternarchusNew spinal cordNeuronal identityNeurogenesis in tissue cultures of adult teleost spinal cord.
Anderson M, Waxman S. Neurogenesis in tissue cultures of adult teleost spinal cord. Brain Research 1985, 352: 203-12. PMID: 4027666, DOI: 10.1016/0165-3806(85)90107-5.Peer-Reviewed Original Research
1984
Postnatal differentiation of rat optic nerve fibers: Electron microscopic observations on the development of nodes of Ranvier and axoglial relations
Hildebrand C, Waxman S. Postnatal differentiation of rat optic nerve fibers: Electron microscopic observations on the development of nodes of Ranvier and axoglial relations. The Journal Of Comparative Neurology 1984, 224: 25-37. PMID: 6715578, DOI: 10.1002/cne.902240103.Peer-Reviewed Original ResearchConceptsRat optic nerve fibersOptic nerve fibersNerve fibersUnmyelinated optic nerve axonsPostnatal differentiationOptic nerve axonsPerinodal astrocytic processesAxoglial signallingNodes of RanvierVesiculotubular profilesOptic nerveRat pupsCompact myelin sheathAxolemmal undercoatingAstrocytic processesNerve axonsAxonal diameterMyelin sheathAxon segmentsAxonsAxolemmaRanvierDaysElectron microscopic observationsFunctional differentiation
1983
Long-term regenerated nerve fibres retain sensitivity to potassium channel blocking agents
Kocsis J, Waxman S. Long-term regenerated nerve fibres retain sensitivity to potassium channel blocking agents. Nature 1983, 304: 640-642. PMID: 6308475, DOI: 10.1038/304640a0.Peer-Reviewed Original ResearchMeSH Keywords4-AminopyridineAction PotentialsAminopyridinesAnimalsCell DifferentiationIon ChannelsMiceNerve Fibers, MyelinatedNerve RegenerationConceptsNerve fibersPotassium channelsMyelinated peripheral nerve fibresAxon segmentsPeripheral nerve fibersAxon sproutsEndoneurial tubesNerve crushFunctional recoveryFunctional organizationMyelinated fibersAxon cylindersSchwann cellsBurst activityMyelinated axonsMammalian axonsAxonsPeripheral connectionsMembrane depolarizationBasement membraneK channelsRegenerated fibersAxon maturation
1980
Development of the axon membrane during differentiation of myelinated fibres in spinal nerve roots
Waxman S, Foster R. Development of the axon membrane during differentiation of myelinated fibres in spinal nerve roots. Proceedings Of The Royal Society B 1980, 209: 441-446. PMID: 6161376, DOI: 10.1098/rspb.1980.0105.Peer-Reviewed Original Research
1972
MORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS
Waxman S, Pappas G, Bennett M. MORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS. Journal Of Cell Biology 1972, 53: 210-224. PMID: 5013596, PMCID: PMC2108696, DOI: 10.1083/jcb.53.1.210.Peer-Reviewed Original ResearchConceptsNodes of RanvierTypical nodeMorphological correlatesSurface areaMicroSingle nerve fibersElectron microscopyLarge nodesPacked layerSeries capacitySpinal neuronsTypical structureNerve fibersElectric organLevel of entrySingle fiberMembrane surface areaNeural originRunning segmentsAxonsNodal morphologyFiber axisFibersTypical appearanceUnique neural systems