2009
Multiple Sclerosis
Preiningerova J, Bomprezzi R, Vollmer T, Waxman S. Multiple Sclerosis. 2009 DOI: 10.1002/9780470015902.a0000192.pub2.Peer-Reviewed Original ResearchCentral nervous systemMagnetic resonance imagingMultiple sclerosisImmune attackMS patientsNeurological disabilityInflammatory diseasesT cellsNervous systemTreatment of MSPathogenesis of MSProgression of MSBrain magnetic resonance imagingYoung womenAutoaggressive T cellsRegulatory T cellsLong-term disabilityDiseases of myelinMajor advancesDisease activityOngoing inflammationImmunotherapeutic strategiesAutoimmune diseasesClinical appearanceHumoral mechanisms
2005
Characterizing the Mechanisms of Progression in Multiple Sclerosis: Evidence and New Hypotheses for Future Directions
Frohman E, Filippi M, Stuve O, Waxman S, Corboy J, Phillips J, Lucchinetti C, Wilken J, Karandikar N, Hemmer B, Monson N, De Keyser J, Hartung H, Steinman L, Oksenberg J, Cree B, Hauser S, Racke M. Characterizing the Mechanisms of Progression in Multiple Sclerosis: Evidence and New Hypotheses for Future Directions. JAMA Neurology 2005, 62: 1345-1356. PMID: 16157741, DOI: 10.1001/archneur.62.9.1345.Peer-Reviewed Original ResearchConceptsMultiple sclerosisProgression of MSCause of progressionMechanisms of progressionMS exacerbationDisease courseInflammatory cascadeClinical manifestationsTherapeutic strategiesDisease processTreatment interventionsEvidence-based observationsEmergence of disabilityProgressionDiseasePotential mechanismsTreatment effectsSclerosisProgressive stagesNovel research initiativesExacerbationTherapyIllnessMajor advancementsExpert perspectives