2003
Selective expression of a persistent Ttx-resistant Na+ current and Navl.9 subunit in myenteric sensory neurons
Rugiero F, Clerc N, Mistry M, Sage D, Black J, Waxman S, Crest M, Delmas P, Gola M. Selective expression of a persistent Ttx-resistant Na+ current and Navl.9 subunit in myenteric sensory neurons. Gastroenterology 2003, 124: a343. DOI: 10.1016/s0016-5085(03)81730-4.Peer-Reviewed Original Research
2002
Nitric Oxide Blocks Fast, Slow, and Persistent Na+ Channels in C-Type DRG Neurons by S-Nitrosylation
Renganathan M, Cummins T, Waxman S. Nitric Oxide Blocks Fast, Slow, and Persistent Na+ Channels in C-Type DRG Neurons by S-Nitrosylation. Journal Of Neurophysiology 2002, 87: 761-775. PMID: 11826045, DOI: 10.1152/jn.00369.2001.Peer-Reviewed Original ResearchConceptsSteady-state voltage-dependent inactivationDorsal root ganglion neuronsNitric oxide blockIncubation of neuronsNO scavenger hemoglobinSlow sodium channel inactivationNitric oxide donorFast TTXMembrane-permeable analogSlow TTXVoltage-dependent inactivationDRG neuronsGanglion neuronsSodium channel inactivationCurrent inhibitionOxide donorScavenger hemoglobinPersistent TTXPAPA-NONOateS-nitrosoTTXNeuronsChannel inactivationSlow inactivationCGMP-dependent protein kinase