22 Neuronal Blocking Factors in Demyelinating Diseases
Cummins T, Waxman S. 22 Neuronal Blocking Factors in Demyelinating Diseases. 2005, 317-326. DOI: 10.1016/b978-012738761-1/50023-7.Peer-Reviewed Original ResearchVoltage-gated sodium channelsGuillain-Barré syndromeMultiple sclerosisSodium channelsChronic inflammatory demyelinating polyneuropathyInflammatory demyelinating polyneuropathyInflammatory demyelinating diseaseBlocking factorsDemyelinating polyneuropathyDemyelinating diseaseClinical deficitsAxonal degenerationInflammatory diseasesConduction blockSodium currentNitric oxideExperimental modelDiseaseImpulse transmissionSclerosisBiological toxinsDemyelinationFactorsPolyneuropathyCytokines29 Blocking the Axonal Injury Cascade Neuroprotection in Multiple Sclerosis and Its Models
Waxman S, Lo A. 29 Blocking the Axonal Injury Cascade Neuroprotection in Multiple Sclerosis and Its Models. 2005, 435-449. DOI: 10.1016/b978-012738761-1/50030-4.Peer-Reviewed Original ResearchExperimental autoimmune encephalomyelitisWhite matter injuryAxonal injuryChannel blockersNitric oxideNon-glucocorticoid steroidsCalcium channel blockersHuman multiple sclerosis lesionsSodium channel blockersMultiple sclerosis lesionsEffects of drugsAutoimmune encephalomyelitisMS pathologyOptic nerveMultiple sclerosisFunctional outcomeNeuroprotective agentsΓ-aminobutyric acidHypoxic injuryPathological evidenceSpinal nervesSpinal cordAdrenergic receptorsVivo preparationSclerosis lesions19 Molecular Mechanisms of Calcium Influx in Axonal Degeneration
Stys P, Waxman S. 19 Molecular Mechanisms of Calcium Influx in Axonal Degeneration. 2005, 275-292. DOI: 10.1016/b978-012738761-1/50020-1.Peer-Reviewed Original ResearchExperimental autoimmune encephalomyelitisAxonal degenerationMultiple sclerosisAxonal injuryCalcium influxInflammatory central nervous system disordersCentral nervous system disordersAcute axonal injuryPotential neuroprotective strategiesWhite matter injuryCellular calcium overloadNervous system disordersAutoimmune encephalomyelitisAxonal damageNeuroprotective strategiesGlutamate releasePathophysiological mechanismsCa overloadCalcium overloadSystem disordersInadequate deliveryMyelinated axonsAberrant operationNitric oxideCa channels