2003
Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury
Hains B, Black J, Waxman S. Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury. The Journal Of Comparative Neurology 2003, 462: 328-341. PMID: 12794736, DOI: 10.1002/cne.10733.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCortical motor neuronsFluoro-GoldCorticospinal tractCord injuryMotor neuronsTerminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphateAdult male Sprague-Dawley ratsRetrograde tracer Fluoro-GoldMale Sprague-Dawley ratsApoptotic cell deathDorsal corticospinal tractPrimary motor cortexTracer Fluoro-GoldSprague-Dawley ratsVoluntary motor controlTUNEL-positive cellsCell deathEvidence of apoptosisSham surgeryDorsal funiculusMotor cortexPyramidal cellsLesion sitePositive cells
1988
Nonpyramidal Motor Systems and Functional Recovery After Damage to the Central Nervous System
Waxman S. Nonpyramidal Motor Systems and Functional Recovery After Damage to the Central Nervous System. Neurorehabilitation And Neural Repair 1988, 2: 1-6. DOI: 10.1177/136140968800200101.Peer-Reviewed Original ResearchLateral corticospinal tractCentral nervous systemCorticospinal tractProximal musculatureNervous systemMotor systemProximal limb musculatureResidual motor functionMotor controlCorticobulbar pathwaysMost patientsDistal musclesCortical lesionsFunctional recoveryBilateral innervationMotor cortexMotor functionMotor neuronsMaintenance of postureClinical observationsUnilateral damageBilateral damagePatientsNeurological diseasesMotor response