1997
Regulation of Na+ channel β1 and β2 subunit mRNA levels in cultured rat astrocytes
Oh Y, Lee Y, Waxman S. Regulation of Na+ channel β1 and β2 subunit mRNA levels in cultured rat astrocytes. Neuroscience Letters 1997, 234: 107-110. PMID: 9364509, DOI: 10.1016/s0304-3940(97)00694-0.Peer-Reviewed Original ResearchConceptsReverse transcription-polymerase chain reactionMRNA levelsSpinal cordCompetitive reverse transcription-polymerase chain reactionQuantitative competitive reverse transcription-polymerase chain reactionSpinal cord astrocytesRat optic nerveDibutyryl cAMPBeta 2 mRNACultured rat astrocytesTranscription-polymerase chain reactionBeta 1 mRNASubunit mRNA levelsNeuroblastoma cell linesOptic nerveChannel β1Cultured astrocytesRat astrocytesCalcium ionophoreAstrocytesBeta 1Chain reactionCell linesCordMRNA
1995
Na+ channel β1 subunit mRNA: differential expression in rat spinal sensory neurons
Oh Y, Sashihara S, Black J, Waxman S. Na+ channel β1 subunit mRNA: differential expression in rat spinal sensory neurons. Brain Research 1995, 30: 357-361. PMID: 7637585, DOI: 10.1016/0169-328x(95)00052-t.Peer-Reviewed Original ResearchConceptsDRG neuronsNervous systemChannel beta 1 subunit (Na beta 1) mRNARat dorsal root ganglion neuronsCell bodiesDorsal root ganglion neuronsSubunit mRNAsBeta 1 mRNA expressionRat central nervous systemSmall DRG neuronsLarge DRG neuronsSpinal sensory neuronsPeripheral nervous systemPostnatal day 4Central nervous systemBeta 1 mRNABeta 1 subunit mRNASitu hybridization histochemistryAdult DRGGanglion neuronsSensory neuronsDay 4Hybridization histochemistryMRNA expressionNeuronsDifferential up-regulation of sodium channel α- and β1-subunit mRNAs in cultured embryonic DRG neurons following exposure to NGF
Zur K, Oh Y, Waxman S, Black J. Differential up-regulation of sodium channel α- and β1-subunit mRNAs in cultured embryonic DRG neurons following exposure to NGF. Brain Research 1995, 30: 97-105. PMID: 7609649, DOI: 10.1016/0169-328x(94)00283-k.Peer-Reviewed Original ResearchConceptsSodium channel alphaNerve growth factorChannel alphaDRG neuronsCultured embryonic DRG neuronsΒ1 subunit mRNAPattern of expressionDorsal root ganglion neuronsSodium channel subunitsEmbryonic DRG neuronsPresence of NGFSitu hybridization cytochemistryAbsence of NGFBeta 1 mRNABeta-subunit mRNANAG mRNAChannel subunitsDevelopment proceedsSodium channel αE16 embryosGanglion neuronsMRNAAlpha-IIIChannel αAlpha IIDifferential Na+ channel β1 subunit mRNA expression in stellate and flat astrocytes cultured from rat cortex and cerebellum: A combined in situ hybridization and immunocytochemistry study
Oh Y, Waxman S. Differential Na+ channel β1 subunit mRNA expression in stellate and flat astrocytes cultured from rat cortex and cerebellum: A combined in situ hybridization and immunocytochemistry study. Glia 1995, 13: 166-173. PMID: 7782102, DOI: 10.1002/glia.440130303.Peer-Reviewed Original ResearchConceptsGFAP-positive astrocytesRat brainChannel beta 1 subunit (Na beta 1) mRNAMRNA expressionBeta 1 mRNA expressionSubunit mRNA expressionBeta 1 mRNABeta 1 subunit mRNARat cortexGranule cellsStellate astrocytesRat astrocytesAstrocytesChannel mRNAImmunocytochemistry methodSubunit mRNAsImmunocytochemistry studiesCerebellumBrainMRNASitu hybridizationRecent studiesDifferential expressionExpressionCells
1994
In situ hybridization localization of the Na+ channel β1 subunit mRNA in rat CNS neurons
Oh Y, Sashihara S, Waxman S. In situ hybridization localization of the Na+ channel β1 subunit mRNA in rat CNS neurons. Neuroscience Letters 1994, 176: 119-122. PMID: 7970226, DOI: 10.1016/0304-3940(94)90885-0.Peer-Reviewed Original ResearchConceptsBeta 1 mRNASpinal cordGranule cellsChannel beta 1 subunit (Na beta 1) mRNABeta 1 mRNA expressionDentate granule cellsAdult rat hippocampusCA1 pyramidal cellsRat CNS neuronsBeta 1 subunit mRNASitu hybridization histochemistryCNS neuronsPyramidal cellsRat hippocampusSitu hybridization localizationChannel β1Gray matterHybridization histochemistryPurkinje cellsMRNA expressionSubunit mRNAsModerate expressionDifferent neuronsStrong expressionNeurons