1994
Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca2+-mediated injury in myelinated CNS axons
Waxman S, Black J, Ransom B, Stys P. Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca2+-mediated injury in myelinated CNS axons. Brain Research 1994, 644: 197-204. PMID: 8050031, DOI: 10.1016/0006-8993(94)91680-2.Peer-Reviewed Original ResearchConceptsOptic nerveOptic nerve axonsRat optic nerveNerve axonsBrain slice chamberCompound action potentialLoss of cristaeMicroM tetrodotoxinAnoxic injuryNormoxic controlsNerveAstrocyte processesPerinodal astrocyte processesWhite matterMyelinated axonsAstrocytic processesCNS axonsTetrodotoxinAction potentialsSlice chamberAxonsLoss of microtubulesCytoskeletal damageInjuryNormoxic conditions
1985
Axo-glial relations in the retina-optic nerve junction of the adult rat: electron-microscopic observations
Hildebrand C, Remahl S, Waxman S. Axo-glial relations in the retina-optic nerve junction of the adult rat: electron-microscopic observations. Brain Cell Biology 1985, 14: 597-617. PMID: 4067610, DOI: 10.1007/bf01200800.Peer-Reviewed Original ResearchConceptsNerve junctionAdult ratsAstrocytic processesDeficient blood-brain barrierEctopic Schwann cellsFibrous astrocytic processesBlood-brain barrierAxo-glial contactsMyelination of axonsNumerous pinocytotic vesiclesTypical oligodendrocytesGlial ensheathmentGlial cellsUnmyelinated segmentsGlia limitansSchwann cellsUnmyelinated axonsWide perivascular spacesPia materPerivascular spacesOligodendroglial cellsDeficient proliferationUnmyelinated partMyelin sheathSame axonPerinodal astrocytic processes at nodes of ranvier in developing normal and glial cell deficient rat spinal cord
Sims T, Waxman S, Black J, Gilmore S. Perinodal astrocytic processes at nodes of ranvier in developing normal and glial cell deficient rat spinal cord. Brain Research 1985, 337: 321-331. PMID: 4027576, DOI: 10.1016/0006-8993(85)90069-1.Peer-Reviewed Original ResearchConceptsPerinodal astrocytic processesLumbar spinal cordSpinal cordGlial cellsAstrocytic processesNodes of RanvierThird postnatal dayRat spinal cordSpinal cord axonsIrradiated spinal cordStages of myelinationAstrocyte involvementVentral funiculusNeuronal elementsPostnatal dayOligodendrocyte populationCentral myelinCordAstrocytesProfound reductionMyelin sheathAxonsRatsNodal axolemmaPresumptive role
1984
Glial fibrillary acidic protein in regenerating teleost spinal cord.
Anderson M, Swanson K, Waxman S, Eng L. Glial fibrillary acidic protein in regenerating teleost spinal cord. Journal Of Histochemistry & Cytochemistry 1984, 32: 1099-1106. PMID: 6481149, DOI: 10.1177/32.10.6481149.Peer-Reviewed Original ResearchConceptsGlial fibrillary acidic proteinSpinal cordFibrillary acidic proteinRegenerated cordPositive stainingAcidic proteinPresence of GFAPTeleost spinal cordNeuronal cell bodiesRegeneration of neuritesGFAP stainingReactive astrocytesAstrocytic profilesNeuronal regenerationGoldfish brainAstrocytic processesCordCell bodiesUltrastructural studyGoldfish Carassius auratusStainingSternarchus albifronsBrainCarassius auratusAstrocytesPostnatal differentiation of rat optic nerve fibers: Electron microscopic observations on the development of nodes of Ranvier and axoglial relations
Hildebrand C, Waxman S. Postnatal differentiation of rat optic nerve fibers: Electron microscopic observations on the development of nodes of Ranvier and axoglial relations. The Journal Of Comparative Neurology 1984, 224: 25-37. PMID: 6715578, DOI: 10.1002/cne.902240103.Peer-Reviewed Original ResearchConceptsRat optic nerve fibersOptic nerve fibersNerve fibersUnmyelinated optic nerve axonsPostnatal differentiationOptic nerve axonsPerinodal astrocytic processesAxoglial signallingNodes of RanvierVesiculotubular profilesOptic nerveRat pupsCompact myelin sheathAxolemmal undercoatingAstrocytic processesNerve axonsAxonal diameterMyelin sheathAxon segmentsAxonsAxolemmaRanvierDaysElectron microscopic observationsFunctional differentiation
1983
Regional node-like membrane specializations in non-myelinated axons of rat retinal nerve fiber layer
Hildebrand C, Waxman S. Regional node-like membrane specializations in non-myelinated axons of rat retinal nerve fiber layer. Brain Research 1983, 258: 23-32. PMID: 24010160, DOI: 10.1016/0006-8993(83)91222-2.Peer-Reviewed Original ResearchConceptsNerve fiber layerInitial axon segmentNon-myelinated axonsAxon segmentsGlial processesFiber layerRetinal nerve fiber layerMembrane specializationsRetinal ganglion cellsAdult rat retinaNodes of RanvierRat retinal nerve fiber layerOptic nerveGanglion cellsMuller cellsRat retinaAstrocytic processesAxonsAxon circumferenceLimited proportionCell processes