1987
Angiotensin converting enzyme immunohistochemistry in rat brain and pituitary gland: Correlation of isozyme type with cellular localization
Strittmatter SM, Snyder SH. Angiotensin converting enzyme immunohistochemistry in rat brain and pituitary gland: Correlation of isozyme type with cellular localization. Neuroscience 1987, 21: 407-420. PMID: 3039401, DOI: 10.1016/0306-4522(87)90131-x.Peer-Reviewed Original ResearchConceptsAngiotensin converting enzymeSubstantia nigraRat brainChoroid plexusPituitary glandPosterior pituitaryConverting enzymePituitary stalk sectionEntopeduncular nucleusSubfornical organCaudate putamenGlobus pallidusEnzyme immunoreactivityParaventricular nucleusAnterior pituitaryAngiotensinEnzyme inhibitorsPosterior lobeIntense stainingCell bodiesMonoclonal antibodiesDiffuse stainingEndothelial cellsEnzyme immunohistochemistryAntibody specificity
1986
Parkinson's disease: Nigral receptor changes support peptidergic role in nigrostriatal modulation
Uhl G, Hackney G, Torchia M, Stranov V, Tourtellotte W, Whitehouse P, Tran V, Strittmatter S. Parkinson's disease: Nigral receptor changes support peptidergic role in nigrostriatal modulation. Annals Of Neurology 1986, 20: 194-203. PMID: 3019228, DOI: 10.1002/ana.410200204.Peer-Reviewed Original ResearchConceptsKappa-opiate receptorsIdiopathic Parkinson's diseaseNormal human brainNigrostriatal circuitryPeptidergic influencesReceptor changesSubstantia nigraMore modest reductionsSerotonin receptorsParkinson's diseaseBenzodiazepine receptorsAutoradiographic studyModest reductionReceptorsAngiotensinSomatostatinHuman brainDiseaseDopamineBenzodiazepines IPatientsNeurotensinSubtypesBrainNigra
1984
Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway.
Strittmatter SM, Lo MM, Javitch JA, Snyder SH. Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway. Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 1599-1603. PMID: 6324207, PMCID: PMC344885, DOI: 10.1073/pnas.81.5.1599.Peer-Reviewed Original ResearchConceptsCaudate putamenSubstantia nigraStriatonigral pathwayRat brainAngiotensin II involvementIpsilateral caudate putamenTrans-synaptic changesIpsilateral substantia nigraMedian preoptic areaAngiotensin-converting enzymeLack of effectStriatal interneuronsAngiotensin IIEntopeduncular nucleusNeuronal perikaryaSubfornical organZona reticulataGlobus pallidusACE activityLocus coeruleusParaventricular nucleusPreoptic areaIbotenic acidMedial habenulaNeuronal pathways