Stephanie Nichols-Burns, PhD, MS, HCLD
Associate Research ScientistCards
Contact Info
About
Titles
Associate Research Scientist
Biography
Stephanie M. Nichols-Burns, PhD, joined Yale Fertility Center in 2017. She is an Associate Research Scientist and the IVF Laboratory Director of Research. She obtained her BS in Biology from The College of William and Mary, an MS in Marine Science from Moss Landing Marine Laboratories studying shark reproduction and early development, and her PhD at the University of New Orleans under one of the pioneers of human IVF. Her doctoral studies investigated aging effects on oocyte quality and reproductive senescence in a non-human primate model (macaques). After spending several years at the Caribbean Primate Research Center Reproductive Biology Program in Puerto Rico, she relocated overseas and investigated ovarian tissue cryopreservation in Erlangen, Germany with the first group in Germany to produce a live birth following reimplantation of cryopreserved ovarian tissue into a cancer survivor. Following these research experiences, she made a natural transition into clinical IVF where she has been able to apply her gained knowledge to helping patients achieve their dreams of parenthood.
Dr. Nichols-Burns is an active member of the American Society of Reproductive Medicine (ASRM), Society for Assisted Reproductive Technology (SART), Society of Reproductive Biologists and Technologists (SRBT), and New York Metropolitan Embryologist Society (NYMES). She is a member of the SART Executive Council as Chair of the Validation Committee. She is also a member of the SART Education Committee and Chair of the SRBT Education Committee. In addition, she participates in collaborative research, serves as a reviewer for multiple journals, and has published several original, peer-reviewed research articles.
Appointments
Obstetrics, Gynecology & Reproductive Sciences
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of New Orleans (2007)
- MS
- San Jose State University (2001)
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Cihan Halicigil, HCLD, PhD, MSc
Murat Basar, PhD
David Seifer, MD
Karen Jubanyik, MD
Mursal Gardezi, MD
Xiao-Bing Gao, PhD
Publications
2024
Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space
Chaplia O, Mathyk B, Nichols-Burns S, Basar M, Halicigil C. Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space. Reproductive Biology And Endocrinology 2024, 22: 123. PMID: 39394617, PMCID: PMC11468284, DOI: 10.1186/s12958-024-01290-y.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsAssisted reproductive technologyIn vitro embryo developmentReproductive technologyRadiation-induced damageGamete handlingClinical embryologistsReproductive endocrinologistsTemperature limitEmbryo cultureReproductive medicineLow Earth orbitEmbryo developmentDeep space travelEarth orbitSpace environmentInterplanetary speciesEarth-boundMicrofluidic devicesCryopreservationEXAMINING RELEVANCE OF AGE AND BODY MASS INDEX FOR EMBRYO MORPHOKINETICS
Dzienny A, Wesevich V, Nichols-Burns S, Chaplia O, Basar M, Unsal E, Halicigil C, Pal L. EXAMINING RELEVANCE OF AGE AND BODY MASS INDEX FOR EMBRYO MORPHOKINETICS. Fertility And Sterility 2024, 122: e195. DOI: 10.1016/j.fertnstert.2024.07.652.Peer-Reviewed Original ResearchEVALUATING THE EFFECTIVENESS OF CONVENTIONAL IVF IN CASES WITH LOW OOCYTE YIELD AND ADVANCED MATERNAL AGE (AMA)
Nichols-Burns S, Chaplia O, Unsal E, Basar M, Halicigil C. EVALUATING THE EFFECTIVENESS OF CONVENTIONAL IVF IN CASES WITH LOW OOCYTE YIELD AND ADVANCED MATERNAL AGE (AMA). Fertility And Sterility 2024, 122: e287-e288. DOI: 10.1016/j.fertnstert.2024.07.891.Peer-Reviewed Original ResearchTHE IMPACT OF ENDOMETRIAL AND EMBRYO RELATED FACTORS ON CLINICAL OUTCOMES AND LIVE BIRTH IN PROGRAMMED AND MODIFIED NATURAL FET CYCLES WITH EUPLOID EMBRYO TRANSFERS
Halicigil C, Basar M, Chaplia O, Nichols-Burns S. THE IMPACT OF ENDOMETRIAL AND EMBRYO RELATED FACTORS ON CLINICAL OUTCOMES AND LIVE BIRTH IN PROGRAMMED AND MODIFIED NATURAL FET CYCLES WITH EUPLOID EMBRYO TRANSFERS. Fertility And Sterility 2024, 122: e65. DOI: 10.1016/j.fertnstert.2024.07.249.Peer-Reviewed Original ResearchSERUM ANTI-MULLERIAN HORMONE IS ASSOCIATED WITH PREOVULATORY FOLLICLE CUMULUS CELL MITOCHONDRIAL DNA COPY NUMBER
Volovsky M, Seifer D, Sahin G, Chaplia O, Nichols-Burns S, Basar M, Seli E, Halicigil C. SERUM ANTI-MULLERIAN HORMONE IS ASSOCIATED WITH PREOVULATORY FOLLICLE CUMULUS CELL MITOCHONDRIAL DNA COPY NUMBER. Fertility And Sterility 2024, 122: e199. DOI: 10.1016/j.fertnstert.2024.07.662.Peer-Reviewed Original Research
2022
FROM OOCYTES TO A LIVE BIRTH: DOES PGT-A HELP OR HARM?
Sabbagh R, S N, Halicigil C, Quinlan J, Shah J, Korkidakis A, Penzias A, Patrizio P, Sakkas D. FROM OOCYTES TO A LIVE BIRTH: DOES PGT-A HELP OR HARM? Fertility And Sterility 2022, 118: e10-e11. DOI: 10.1016/j.fertnstert.2022.09.232.Peer-Reviewed Original ResearchICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD
Beroukhim G, Seifer D, Chaplia O, Nichols-Burns S, Basar M, Halicigil C. ICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD. Fertility And Sterility 2022, 118: e143. DOI: 10.1016/j.fertnstert.2022.08.419.Peer-Reviewed Original Research
2021
Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary pads
Mor A, Gardezi M, Jubanyik K, Simsek B, Seifer DB, Patrizio P, Esencan E, Imamoglu G, Zhang M, Nichols-Burns SM, Taylor HS. Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary pads. Fertility And Sterility 2021, 116: 462-469. PMID: 33461753, DOI: 10.1016/j.fertnstert.2020.10.006.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsExtrauterine pregnancyVaginal bloodAlpha-fetoproteinOngoing pregnancyAFP levelsSanitary padsHigh alpha-fetoprotein levelsOngoing pregnancy groupProspective cohort studyAlpha-fetoprotein levelsAcademic medical centerPregnancy groupCohort studyMiscarriage casesFirst trimesterOffice visitsMedical CenterMAIN OUTCOMEPregnancyMedian levelsMiscarriageBloodAnxiety levelsAFPCharacteristic analysis
2019
A step towards the automation of intracytoplasmic sperm injection: real time confirmation of mouse and human oocyte penetration and viability by electrical resistance measurement
Mor A, Zhang M, Esencan E, Simsek B, Nichols-Burns SM, Liu Y, Lo J, Kelk DA, Flores V, Gao XB, Seli E. A step towards the automation of intracytoplasmic sperm injection: real time confirmation of mouse and human oocyte penetration and viability by electrical resistance measurement. Fertility And Sterility 2019, 113: 234-236. PMID: 31883732, DOI: 10.1016/j.fertnstert.2019.09.023.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIntracytoplasmic sperm injectionICSI pipetteSperm injectionOocyte penetrationIntact oolemmaOocyte retrieval procedureMann-Whitney testMouse oocytesOocyte retrievalFemale miceMAIN OUTCOMEAcademic centersImmature oocytesHuman oocytesMature oocytesObjective toolMiceOocytesWomenVisual assessmentPipetteInjectionOolemmaStep 1GroupDay 2 laser assisted hatching (AH) significantly improves implantation rates in fresh blastocyst transfers
Bjorkman S, Nichols-Burns S, Lo J, Kodaman N, Kodaman P, Kelk D. Day 2 laser assisted hatching (AH) significantly improves implantation rates in fresh blastocyst transfers. Fertility And Sterility 2019, 112: e292. DOI: 10.1016/j.fertnstert.2019.07.856.Peer-Reviewed Original Research