2010
Engineered Disc-Like Angle-Ply Structures for Intervertebral Disc Replacement
Nerurkar NL, Sen S, Huang AH, Elliott DM, Mauck RL. Engineered Disc-Like Angle-Ply Structures for Intervertebral Disc Replacement. Spine 2010, 35: 867-873. PMID: 20354467, PMCID: PMC3421837, DOI: 10.1097/brs.0b013e3181d74414.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsBiomechanical PhenomenaCattleCells, CulturedCompressive StrengthExtracellular MatrixFibrocartilageHumansHydrogelsIntervertebral DiscIntervertebral Disc DisplacementMaterials TestingMesenchymal Stem Cell TransplantationMesenchymal Stem CellsNanofibersProsthesis DesignSepharoseTissue EngineeringTissue ScaffoldsWeight-Bearing
2009
Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus
Nerurkar NL, Baker BM, Sen S, Wible EE, Elliott DM, Mauck RL. Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus. Nature Materials 2009, 8: 986-992. PMID: 19855383, PMCID: PMC3415301, DOI: 10.1038/nmat2558.Peer-Reviewed Original ResearchConceptsMulti-scale structural hierarchyAnnulus fibrosus tissue engineeringTissue engineering applicationsLoad-bearing tissuesTensile responseEngineering applicationsTissue engineeringLaminatesBiomimetic materialsComplex mechanical functionsNative tissueStructural hierarchySuccessful engineeringEngineeringScaffoldsAnnulus fibrosusGreat interestShearingMechanical functionComplex tissuesDepositionMaterials