Intervertebral Disc Function Is Restored in an In Vivo Model of Chronic Nucleus Pulposus Glycosaminoglycan Reduction
Boxberger J, Auerbach J, Sen S, Dodge G, Elliott D. Intervertebral Disc Function Is Restored in an In Vivo Model of Chronic Nucleus Pulposus Glycosaminoglycan Reduction. 2008, 127-128. DOI: 10.1115/sbc2008-192937.Peer-Reviewed Original ResearchWeeks post treatmentDisc degenerationPost treatmentIntervertebral disc degenerationRat lumbar discsLong-term effectsLumbar discVivo modelGAG lossDegenerationEarly lossHallmark featureTerm effectsGAG depletionMechanical functionDetectable changeGagGlycosaminoglycan contentSmall percentageTreatmentLow levelsMechanical changesHuman degenerationElevated stressHypermobility