2012
Human annulus fibrosus dynamic tensile modulus increases with degeneration
Sen S, Jacobs NT, Boxberger JI, Elliott DM. Human annulus fibrosus dynamic tensile modulus increases with degeneration. Mechanics Of Materials 2012, 44: 93-98. PMID: 22247579, PMCID: PMC3254102, DOI: 10.1016/j.mechmat.2011.07.016.Peer-Reviewed Original ResearchDynamic viscoelastic propertiesViscoelastic propertiesDynamic modulusStrain levelsCyclic loading conditionsCyclic tensile loadingLinear viscoelastic modelHigher dynamic modulusTensile modulus increasesPhase angleHuman annulus fibrosusTensile samplesTensile loadingDecreased phase angleLoading conditionsEffect of degenerationUniaxial tensionAnnulus fibrosusViscoelastic modelEquilibrium strainModulus increases
2009
Reduced nucleus pulposus glycosaminoglycan content alters intervertebral disc dynamic viscoelastic mechanics
Boxberger JI, Orlansky AS, Sen S, Elliott DM. Reduced nucleus pulposus glycosaminoglycan content alters intervertebral disc dynamic viscoelastic mechanics. Journal Of Biomechanics 2009, 42: 1941-1946. PMID: 19539936, PMCID: PMC2756063, DOI: 10.1016/j.jbiomech.2009.05.008.Peer-Reviewed Original ResearchConceptsDynamic stiffnessCompressive loadEquilibrium loadHigh dynamic stiffnessDynamic loading regimesPhase angleDynamic viscoelastic propertiesMechanical behaviorAxial loadViscoelastic mechanicsOscillatory loadingLoading regimesLow loadViscoelastic propertiesDynamic mechanicsLumbar motion segmentsMechanical mechanismDisc mechanicsStiffnessLoadSpectrum of frequenciesPossible mechanical mechanismsReduced glycosaminoglycansMotion segmentsMechanics
2008
Effect of Degeneration on the Dynamic Viscoelastic Properties of Human Annulus Fibrosus in Tension
Sen S, Boxberger J, Schroeder Y, Orias A, Elliott D. Effect of Degeneration on the Dynamic Viscoelastic Properties of Human Annulus Fibrosus in Tension. 2008, 609-610. DOI: 10.1115/sbc2008-193057.Peer-Reviewed Original ResearchDisc degenerationViscoelastic propertiesStructural finite element modelIntervertebral disc degenerationFinite element modelUniaxial tensile testsPhysiological cyclic loadingQuasi-static conditionsHuman AF tissueDynamic viscoelastic propertiesStatic viscoelastic propertiesAF tissueCyclic loadingElement modelTensile testsIntervertebral discMechanical assessmentRegenerative approachesTissueDegenerate tissueMechanical functionDegeneration