2016
An RNA-aptamer-based two-color CRISPR labeling system
Wang S, Su JH, Zhang F, Zhuang X. An RNA-aptamer-based two-color CRISPR labeling system. Scientific Reports 2016, 6: 26857. PMID: 27229896, PMCID: PMC4882555, DOI: 10.1038/srep26857.Peer-Reviewed Original ResearchConceptsSingle guide RNAsDifferent fluorescent proteinsGenomic lociFluorescent proteinSpecific chromatin lociEndogenous genomic lociDynamics of chromatinPP7 coat proteinTarget genomic lociStem loop 2Essential biological functionsSpecific DNA sequencesDifferent bacterial speciesChromatin imagingCRISPR single guide RNAsChromatin lociRepetitive sequencesDNA sequencesChromatin labelingCoat proteinBiological functionsHuman cellsLoop 2RNA aptamersBacterial species
2014
Characterization and development of photoactivatable fluorescent proteins for single-molecule–based superresolution imaging
Wang S, Moffitt JR, Dempsey GT, Xie XS, Zhuang X. Characterization and development of photoactivatable fluorescent proteins for single-molecule–based superresolution imaging. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 8452-8457. PMID: 24912163, PMCID: PMC4060684, DOI: 10.1073/pnas.1406593111.Peer-Reviewed Original ResearchAnimalsBacterial ProteinsBlotting, WesternCell Line, TumorChlorocebus aethiopsCOS CellsDNA-Binding ProteinsEscherichia coli ProteinsHumansLuminescent ProteinsMicroscopy, FluorescencePhotonsProtein MultimerizationReceptors, Cell SurfaceRecombinant Fusion ProteinsSpectrometry, FluorescenceVimentinZyxin