Clinical potential of cariprazine in the treatment of acute mania.
Altınbaş K, Guloksuz S, Oral E. Clinical potential of cariprazine in the treatment of acute mania. Psychiatria Danubina 2013, 25: 207-13. PMID: 24048386.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAntipsychotic AgentsBipolar DisorderClinical Trials as TopicHumansPiperazinesConceptsAcute manic episodeAdverse eventsManic episodesTreatment-emergent adverse eventsD3 receptor activityFlexible-dose studyCommon adverse eventsSerious adverse eventsCommon side effectsAdditional therapeutic benefitSecond-generation antipsychoticsCariprazine treatmentDopamine agonismPlacebo armAcute maniaExtrapyramidal symptomsQTc prolongationGeneration antipsychoticsHistamine H1Novel antipsychoticsProlactin increaseMetabolic disturbancesClinical trialsClinical dataDopamine D2