2013
Clinical potential of cariprazine in the treatment of acute mania.
Altınbaş K, Guloksuz S, Oral E. Clinical potential of cariprazine in the treatment of acute mania. Psychiatria Danubina 2013, 25: 207-13. PMID: 24048386.Peer-Reviewed Original ResearchConceptsAcute manic episodeAdverse eventsManic episodesTreatment-emergent adverse eventsD3 receptor activityFlexible-dose studyCommon adverse eventsSerious adverse eventsCommon side effectsAdditional therapeutic benefitSecond-generation antipsychoticsCariprazine treatmentDopamine agonismPlacebo armAcute maniaExtrapyramidal symptomsQTc prolongationGeneration antipsychoticsHistamine H1Novel antipsychoticsProlactin increaseMetabolic disturbancesClinical trialsClinical dataDopamine D2
2010
The treatment of bipolar disorder during pregnancy and the postpartum period.
Gülöksüz S, Akdeniz F, Ince B, Oral E. The treatment of bipolar disorder during pregnancy and the postpartum period. Turkish Journal Of Psychiatry 2010, 21: 155-66. PMID: 20514566, DOI: 10.5080/u6131.Peer-Reviewed Original ResearchConceptsPostpartum periodBipolar disorderPsychotropic medicationsBD patientsOnset of BDRisk of relapseRisk-benefit decisionsNeonatal toxicityPregnant patientsAdverse eventsObstetrical outcomesFetal exposureSafety profileBreast milkPharmacological treatmentPrevent recurrenceTreatment optionsMedication effectsPsychotropic agentsReproductive yearsNeurobehavioral developmentRecurrence increasesPregnancyPatientsMedications