Gut microbiome profiles to exclude the diagnosis of hepatic encephalopathy in patients with cirrhosis
Bajaj J, O’Leary J, Jakab S, Fagan A, Sikaroodi M, Gillevet P. Gut microbiome profiles to exclude the diagnosis of hepatic encephalopathy in patients with cirrhosis. Gut Microbes 2024, 16: 2392880. PMID: 39189586, PMCID: PMC11352695, DOI: 10.1080/19490976.2024.2392880.Peer-Reviewed Original ResearchConceptsGut microbiome profilesHepatic encephalopathyGut microbiota testMicrobial speciesMicrobiome profilesTraining cohortValidation cohortHE diagnosisStool microbiotaMulticenter prospective cohortDiagnosis of hepatic encephalopathyMulticenter validation cohortNeuropsychological testsNanopore analysisSemi-quantitative questionnaireGutStandard neuropsychological testsProspective cohortIdentified patientsPatientsGold standardCohortDisease processCognitive complaintsDiagnosis869 GUT MICROBIOME PROFILE THROUGH MACHINE LEARNING ALGORITHMS CLARIFIES HEPATIC ENCEPHALOPATHY DIAGNOSES IN A MULTI-CENTER CIRRHOSIS COHORT
Bajaj J, O'Leary J, Jakab S, Chong N, Sikaroodi M, Gillevet P. 869 GUT MICROBIOME PROFILE THROUGH MACHINE LEARNING ALGORITHMS CLARIFIES HEPATIC ENCEPHALOPATHY DIAGNOSES IN A MULTI-CENTER CIRRHOSIS COHORT. Gastroenterology 2024, 166: s-200-s-201. DOI: 10.1016/s0016-5085(24)00954-5.Peer-Reviewed Original Research