Conformational Dynamics of Calcium-Triggered Activation of Fusion by Synaptotagmin
Krishnakumar SS, Kümmel D, Jones SJ, Radoff DT, Reinisch KM, Rothman JE. Conformational Dynamics of Calcium-Triggered Activation of Fusion by Synaptotagmin. Biophysical Journal 2013, 105: 2507-2516. PMID: 24314081, PMCID: PMC3853086, DOI: 10.1016/j.bpj.2013.10.029.Peer-Reviewed Original ResearchConceptsC2 domainSynaptotagmin C2 domainsFluorescence resonance energy transfer spectroscopyEnergy transfer spectroscopyRapid exocytosisConformational dynamicsSynaptotagminSynaptic vesiclesLipid bilayersNeurotransmitter releaseSnare