2019
“Radiotherapy for older women (ROW)”: A risk calculator for women with early-stage breast cancer
Wang SY, Abujarad F, Chen T, Evans SB, Killelea BK, Mougalian SS, Fraenkel L, Gross C. “Radiotherapy for older women (ROW)”: A risk calculator for women with early-stage breast cancer. Journal Of Geriatric Oncology 2019, 11: 850-859. PMID: 31899199, PMCID: PMC7263974, DOI: 10.1016/j.jgo.2019.12.010.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerRisk calculatorLocal recurrenceBreast cancerOlder womenTumor characteristicsBreast cancer-specific outcomesReceipt of radiotherapyCancer-specific outcomesEarly breast cancerIndividual patient's riskBenefits of radiotherapyAdvisory CommitteeLife expectancyOnline risk calculatorLong-term survivalShared decision makingBenefit of RTOlder adult womenRadiotherapy statusCause mortalityOverall survivalRecurrence reductionFunctional statusPatient risk
2017
Are Small Breast Cancers Good because They Are Small or Small because They Are Good?
Lannin DR, Wang S. Are Small Breast Cancers Good because They Are Small or Small because They Are Good? New England Journal Of Medicine 2017, 376: 2286-91. PMID: 28591529, DOI: 10.1056/nejmsr1613680.Peer-Reviewed Original ResearchInformation Needs of Older Women With Early-Stage Breast Cancer When Making Radiation Therapy Decisions
Wang SY, Kelly G, Gross C, Killelea BK, Mougalian S, Presley C, Fraenkel L, Evans SB. Information Needs of Older Women With Early-Stage Breast Cancer When Making Radiation Therapy Decisions. International Journal Of Radiation Oncology • Biology • Physics 2017, 98: 733-740. PMID: 28366581, PMCID: PMC5468466, DOI: 10.1016/j.ijrobp.2017.02.001.Peer-Reviewed Original ResearchConceptsRadiation therapy decisionsEarly-stage breast cancerTherapy decisionsOlder womenRadiation therapyBreast cancerSide effectsAdjuvant radiation therapyBreast cancer careBreast cancer survivorsCancer survivorsMean ageCancer careCancer needsResponse rateProfessional Advisory CommitteeTherapyWomenCancerAdvisory CommitteeParticipantsYearsWide variationLumpectomyMain decision makers
2015
Preoperative Breast Magnetic Resonance Imaging and Contralateral Breast Cancer Occurrence Among Older Women With Breast Cancer
Wang SY, Long JB, Killelea BK, Evans SB, Roberts KB, Silber A, Gross CP. Preoperative Breast Magnetic Resonance Imaging and Contralateral Breast Cancer Occurrence Among Older Women With Breast Cancer. Journal Of Clinical Oncology 2015, 34: 321-328. PMID: 26628465, PMCID: PMC4872032, DOI: 10.1200/jco.2015.62.9741.Peer-Reviewed Original ResearchConceptsContralateral breast cancerPreoperative magnetic resonance imagingMagnetic resonance imagingBreast cancerCBC eventsMRI useOlder womenPreoperative breast magnetic resonance imagingOccult contralateral breast cancerResonance imagingStage IIEarly-stage breast cancerPreoperative MRI useBreast magnetic resonance imagingBreast cancer occurrenceSEER-Medicare databaseImpact of detectionDetection rateCumulative incidenceCancer occurrenceStage ICancerPropensity scoreWomenPatients
2014
Understanding Regional Variation in Medicare Expenditures for Initial Episodes of Prostate Cancer Care
Wang SY, Wang R, Yu JB, Ma X, Xu X, Kim SP, Soulos PR, Saraf A, Gross CP. Understanding Regional Variation in Medicare Expenditures for Initial Episodes of Prostate Cancer Care. Medical Care 2014, 52: 680-687. PMID: 25023913, PMCID: PMC4129645, DOI: 10.1097/mlr.0000000000000158.Peer-Reviewed Original ResearchConceptsAncillary proceduresPatient characteristicsTreatment modalitiesTreatment intensityEnd Results-Medicare databaseProstate cancer careSpecific treatment modalitiesContribution of patientHospital referral regionsInitial treatmentCancer careInitial episodeNoncancer controlsProstate cancerQuintile 5Referral regionsSubstantial geographic variationCare costsMedicare expendituresCostly modalityTreatment factorsMean expenditureLowest expenditure quintileSurgeryModalities
2010
Association Between Patient and Tumor Characteristics With Clinical Outcomes in Women With Ductal Carcinoma In Situ
Shamliyan T, Wang SY, Virnig BA, Tuttle TM, Kane RL. Association Between Patient and Tumor Characteristics With Clinical Outcomes in Women With Ductal Carcinoma In Situ. JNCI Monographs 2010, 2010: 121-129. PMID: 20956815, PMCID: PMC5161074, DOI: 10.1093/jncimonographs/lgq034.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedBody Mass IndexBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingFemaleGonadal Steroid HormonesHumansMammographyMenopauseNeoplasm Recurrence, LocalNeoplasms, Hormone-DependentPrognosisRacial GroupsRandomized Controlled Trials as TopicReceptor, ErbB-2Receptors, EstrogenReceptors, ProgesteroneRiskSocioeconomic FactorsTreatment OutcomeTumor BurdenConceptsDuctal carcinomaClinical outcomesRecurrent cancerTumor characteristicsWorse outcomesNegative estrogen receptor statusAdvanced recurrent cancerPositive surgical marginsEstrogen receptor statusLarger tumor sizeHigh-risk categoryComposite prognostic indicesReceptor statusSurgical marginsPrognostic indexTumor sizeComedo necrosisPathological gradingClinical trialsObservational studyHigh riskHER2 receptorSynthesis of evidenceHigh mortalityYoung women