2019
A Value of Information Analysis of Research on the 21-Gene Assay for Breast Cancer Management
Kunst NR, Alarid-Escudero F, Paltiel AD, Wang SY. A Value of Information Analysis of Research on the 21-Gene Assay for Breast Cancer Management. Value In Health 2019, 22: 1102-1110. PMID: 31563252, PMCID: PMC7343670, DOI: 10.1016/j.jval.2019.05.004.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerObservational studyBreast cancerLow-risk early-stage breast cancerHormone receptor-positive early-stage breast cancerPredictive valueLow-risk womenProspective observational studyHigh-risk womenRetrospective observational studyBreast cancer managementQuality-adjusted life yearsCost-effectiveness findingsTraditional risk predictionAdjuvant chemotherapyChemotherapy useAlternative study designsOncotype DXCancer managementClinical utilityCurrent evidenceInsufficient evidenceLife yearsRoutine useStudy design
2016
School breakfast and body mass index: a longitudinal observational study of middle school students
Wang S, Schwartz MB, Shebl FM, Read M, Henderson KE, Ickovics JR. School breakfast and body mass index: a longitudinal observational study of middle school students. Pediatric Obesity 2016, 12: 213-220. PMID: 26989876, PMCID: PMC7075461, DOI: 10.1111/ijpo.12127.Peer-Reviewed Original ResearchConceptsBreakfast eatersRace/ethnicityExcessive weight gainOverweight/obesityBody mass indexLongitudinal observational studyOverall dietLongitudinal analysisSchool breakfastIncreased oddsHealthy weightMass indexBreakfast patternsWeight statusObservational studyIncrease riskWeight gainBreakfastWeight changeSecond breakfastAdditional researchEatersLatent transition analysisYears
2012
Ductal carcinoma in situ, and the influence of the mode of detection, population characteristics, and other risk factors.
Virnig BA, Wang SY, Tuttle TM. Ductal carcinoma in situ, and the influence of the mode of detection, population characteristics, and other risk factors. American Society Of Clinical Oncology Educational Book 2012, 45-8. PMID: 24451706, DOI: 10.14694/edbook_am.2012.32.81.Peer-Reviewed Original ResearchInvasive breast cancerMajor risk factorBreast cancerRisk factorsEndocrine therapyDuctal carcinomaSentinel lymph node biopsyRate of DCISTreatment of DCISLymph node biopsyProgesterone receptor statusWhole breast irradiationRisk of overtreatmentPartial breast irradiationNormal breast tissueDCIS recurrenceHER2 positivityNode biopsyPrognostic factorsReceptor statusInvasive diseaseObservational studyTreatment decisionsDCISCancer
2011
Tumor characteristics as predictors of local recurrence after treatment of ductal carcinoma in situ: a meta-analysis
Wang SY, Shamliyan T, Virnig BA, Kane R. Tumor characteristics as predictors of local recurrence after treatment of ductal carcinoma in situ: a meta-analysis. Breast Cancer Research And Treatment 2011, 127: 1-14. PMID: 21327465, DOI: 10.1007/s10549-011-1387-4.Peer-Reviewed Original ResearchConceptsIpsilateral breast tumor recurrenceHER2/neu receptorTumor characteristicsLocal recurrenceDuctal carcinomaTumor sizeTumor gradeLow-risk DCIS patientsNeu receptorManagement of DCISBreast tumor recurrenceHigh-quality evidenceCourse of treatmentDCIS patientsAggressive treatmentPrognostic factorsSurgical marginsTumor recurrenceSubgroup analysisObservational studyMethod of detectionEligible articlesSystematic reviewRecurrenceDCIS
2010
Association Between Patient and Tumor Characteristics With Clinical Outcomes in Women With Ductal Carcinoma In Situ
Shamliyan T, Wang SY, Virnig BA, Tuttle TM, Kane RL. Association Between Patient and Tumor Characteristics With Clinical Outcomes in Women With Ductal Carcinoma In Situ. JNCI Monographs 2010, 2010: 121-129. PMID: 20956815, PMCID: PMC5161074, DOI: 10.1093/jncimonographs/lgq034.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedBody Mass IndexBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingFemaleGonadal Steroid HormonesHumansMammographyMenopauseNeoplasm Recurrence, LocalNeoplasms, Hormone-DependentPrognosisRacial GroupsRandomized Controlled Trials as TopicReceptor, ErbB-2Receptors, EstrogenReceptors, ProgesteroneRiskSocioeconomic FactorsTreatment OutcomeTumor BurdenConceptsDuctal carcinomaClinical outcomesRecurrent cancerTumor characteristicsWorse outcomesNegative estrogen receptor statusAdvanced recurrent cancerPositive surgical marginsEstrogen receptor statusLarger tumor sizeHigh-risk categoryComposite prognostic indicesReceptor statusSurgical marginsPrognostic indexTumor sizeComedo necrosisPathological gradingClinical trialsObservational studyHigh riskHER2 receptorSynthesis of evidenceHigh mortalityYoung womenThe Impact of Surgery, Radiation, and Systemic Treatment on Outcomes in Patients With Ductal Carcinoma In Situ
Kane RL, Virnig BA, Shamliyan T, Wang SY, Tuttle TM, Wilt TJ. The Impact of Surgery, Radiation, and Systemic Treatment on Outcomes in Patients With Ductal Carcinoma In Situ. JNCI Monographs 2010, 2010: 130-133. PMID: 20956816, PMCID: PMC5161061, DOI: 10.1093/jncimonographs/lgq022.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsAntineoplastic Agents, HormonalAntineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingChemotherapy, AdjuvantCombined Modality TherapyDisease ProgressionFemaleHumansIncidenceMastectomyMastectomy, SegmentalNeoplasm Recurrence, LocalNeoplasms, Second PrimaryPrognosisRadiotherapy, AdjuvantRandomized Controlled Trials as TopicTamoxifenTreatment OutcomeConceptsBreast-conserving surgeryDuctal carcinomaInvasive carcinomaWhole breast radiation therapyImpact of surgeryTerms of recurrenceInvasive recurrenceRecurrent DCISDCIS recurrenceSystemic treatmentObservational studyRadiation therapyEquivalent outcomesCarcinomaMastectomyRecurrenceDCISSurgeryTamoxifenLower ratesOutcomesWomenLumpectomyPatientsMEDLINE