2016
Zika virus productively infects primary human placenta-specific macrophages
Jurado KA, Simoni MK, Tang Z, Uraki R, Hwang J, Householder S, Wu M, Lindenbach BD, Abrahams VM, Guller S, Fikrig E. Zika virus productively infects primary human placenta-specific macrophages. JCI Insight 2016, 1: e88461. PMID: 27595140, PMCID: PMC5007065, DOI: 10.1172/jci.insight.88461.Peer-Reviewed Original ResearchZika virus infectionHofbauer cellsVirus infectionFetal brainZika virusTerm placental villous explantsHuman placental macrophagesPlacental villous explantsPregnancy complicationsPlacental macrophagesPlacental barrierVillous explantsInfectious virusVillous fibroblastsCongenital defectsInfectionStrong associationMigratory activityVirusMacrophagesBrainCell typesCellsComplicationsFlaviviruses
2005
Expression and Regulation of Glucocorticoid Receptor in Human Placental Villous Fibroblasts
Lee MJ, Wang Z, Yee H, Ma Y, Swenson N, Yang L, Kadner SS, Baergen RN, Logan SK, Garabedian MJ, Guller S. Expression and Regulation of Glucocorticoid Receptor in Human Placental Villous Fibroblasts. Endocrinology 2005, 146: 4619-4626. PMID: 16055431, DOI: 10.1210/en.2005-0235.Peer-Reviewed Original ResearchConceptsGC receptorSmooth muscle cellsHuman placentaGR levelsHormone treatmentShort-term GC treatmentMuscle cellsLong-term hormone treatmentVascular smooth muscle cellsGR protein expressionGR mRNA levelsPlacental cell typesNormal term human placentasTotal GR levelsTerm human placentaCell typesGR antibodyGC treatmentHormone exposureStem villiCytotrophoblast cellsGlucocorticoid receptorPlacental fibroblastsTerminal villiVillous fibroblasts