1999
Nucleotide Analog Interference Mapping
Ryder S, Strobel S. Nucleotide Analog Interference Mapping. Methods 1999, 18: 38-50. PMID: 10208815, DOI: 10.1006/meth.1999.0755.Peer-Reviewed Original ResearchConceptsFunctional groupsActive moleculesGroup substitutionNucleotide analog interference mappingIncorporation propertiesIndividual analoguesMoleculesSeries 5AnaloguesSubstitution experimentsGel electrophoresisInterference mappingUnique biochemical signatureSubstitutionSynthesisNucleoside analog triphosphatesActivity assaysBiochemical informationReactionAnalog substitutionsAssayable functionChemogenetic approachRNA structureNucleotide analoguesIodineA hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme
Strobel S, Ortoleva-Donnelly L. A hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme. Cell Chemical Biology 1999, 6: 153-165. PMID: 10074469, DOI: 10.1016/s1074-5521(99)89007-3.Peer-Reviewed Original Research
1988
Triticone A: A novel bioactive lactam with potential as a molecular probe
Kenfield D, Strobel S, Sugawara F, Berglund D, Strobel G. Triticone A: A novel bioactive lactam with potential as a molecular probe. Biochemical And Biophysical Research Communications 1988, 157: 174-182. PMID: 3196330, DOI: 10.1016/s0006-291x(88)80029-9.Peer-Reviewed Original ResearchConceptsPlant pathogenic fungiMolecular probesProtoplast assaysSH functional groupsCO2 fixation reactionWheat cellsPathogenic fungiPhysiological functionsSpirocyclic lactamsFunctional groupsActive siteEnantiomeric mixturesNovel compoundsFluorescein diacetateBiological activityFixation reactionBiological systemsAccurate quantitationLactamsPhotosynthesisProtoplastsChlorosisFungiPlantsWheat