1164. Epidemiology of Cryptococcal Infections in Non-HIV Patients: A 20-year Single Center Experience
Kumar R, Nam H, Roberts S, Penugonda S, Angarone M, Stosor V. 1164. Epidemiology of Cryptococcal Infections in Non-HIV Patients: A 20-year Single Center Experience. Open Forum Infectious Diseases 2020, 7: s608-s608. PMCID: PMC7776216, DOI: 10.1093/ofid/ofaa439.1350.Peer-Reviewed Original ResearchCryptococcal antigenRisk factorsCerebrospinal fluidSingle-center retrospective cohort studyCenter retrospective cohort studySolid organ transplant recipientsCommon predisposing conditionsNon-HIV patientsPositive cryptococcal antigenPositive culture dataRetrospective cohort studyChronic kidney diseaseOrgan transplant recipientsSingle-center experienceSolid organ transplantsTime of diagnosisUse of immunosuppressionNorthwestern Memorial HospitalCentral nervous systemSite of infectionHospital mortalityCryptococcal infectionTransplant recipientsCohort studyPredisposing conditionA clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways
Lorenzo-Redondo R, Nam HH, Roberts SC, Simons LM, Jennings LJ, Qi C, Achenbach CJ, Hauser AR, Ison MG, Hultquist JF, Ozer EA. A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways. EBioMedicine 2020, 62: 103112. PMID: 33186810, PMCID: PMC7655495, DOI: 10.1016/j.ebiom.2020.103112.Peer-Reviewed Original ResearchConceptsPatient's upper airwayViral loadSARS-CoV-2Upper airwayHighest average viral loadSARS-CoV-2 infectionTranslational Research AwardTime of diagnosisAverage viral loadCOVID-19 patientsLow viral loadComprehensive cancer centerCoronavirus disease 2019SARS-CoV-2 isolatesSARS-CoV-2 virusClade 1 virusesClade 2 virusesRelative viral loadVirologic featuresClinical characteristicsClinical parametersCancer CenterDistinct viral cladesClinical significanceTranslational Science Institute