2015
Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study
Murad K, Goff DC, Morgan TM, Burke GL, Bartz TM, Kizer JR, Chaudhry SI, Gottdiener JS, Kitzman DW. Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study. JACC Heart Failure 2015, 3: 542-550. PMID: 26160370, PMCID: PMC4499113, DOI: 10.1016/j.jchf.2015.03.004.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAtrial FibrillationCognition DisordersCohort StudiesComorbidityCoronary DiseaseFemaleHeart FailureHumansHypertensionIncidenceLongitudinal StudiesMalePeripheral Arterial DiseasePhysical FitnessPrevalenceProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveConceptsIncident heart failureCardiovascular Health StudyHeart failureGreater mortality riskMortality riskPercent of participantsCognitive impairmentElderly patientsFunctional impairmentDaily livingHealth StudyBurden of comorbiditiesChronic kidney diseaseMultivariable-adjusted modelsTotal mortality riskRelevant comorbiditiesDiabetes mellitusInitial diagnosisCerebrovascular diseaseKidney diseaseMean ageHigh burdenComorbiditiesInstrumental activitiesMortality rate
2011
Change in Comorbidity Prevalence with Advancing Age Among Persons with Heart Failure
Ahluwalia SC, Gross CP, Chaudhry SI, Leo-Summers L, Van Ness PH, Fried TR. Change in Comorbidity Prevalence with Advancing Age Among Persons with Heart Failure. Journal Of General Internal Medicine 2011, 26: 1145-1151. PMID: 21573881, PMCID: PMC3181289, DOI: 10.1007/s11606-011-1725-6.Peer-Reviewed Original ResearchConceptsHeart failureDiscordant comorbiditiesComorbidity burdenMedicare beneficiariesDiscordant conditionsOlder personsChronic Conditions WarehouseCount of conditionsOverall comorbidity burdenHigher overall burdenOlder Medicare beneficiariesPatterns of comorbidityComorbidity prevalencePrimary illnessPrevalence increasesOverall burdenMedian numberComorbiditiesGreater prevalenceAge strataConcordant conditionsPrevalenceUnrelated conditionsOverall managementOlder beneficiariesTrends in Comorbidity, Disability, and Polypharmacy in Heart Failure
Wong CY, Chaudhry SI, Desai MM, Krumholz HM. Trends in Comorbidity, Disability, and Polypharmacy in Heart Failure. The American Journal Of Medicine 2011, 124: 136-143. PMID: 21295193, PMCID: PMC3237399, DOI: 10.1016/j.amjmed.2010.08.017.Peer-Reviewed Original ResearchConceptsProportion of patientsHeart failureSelf-reported heart failureHeart failure populationComorbid chronic conditionsNumber of comorbiditiesNutrition Examination SurveyCare of patientsPrevalence of disabilityPhenotype of patientsComplexity of patientsMedication useRecent patientsFunctional disabilityExamination SurveyFailure populationPhysical functionPrescription medicationsPatient preferencesChronic conditionsNational HealthPatient's abilityComorbiditiesPatientsOlder individuals
2005
Do Age and Comorbidity Affect Intensity of Pharmacological Therapy for Poorly Controlled Diabetes Mellitus?
Chaudhry SI, Berlowitz DR, Concato J. Do Age and Comorbidity Affect Intensity of Pharmacological Therapy for Poorly Controlled Diabetes Mellitus? Journal Of The American Geriatrics Society 2005, 53: 1214-1216. PMID: 16108941, DOI: 10.1111/j.1532-5415.2005.53370.x.Peer-Reviewed Original ResearchConceptsDiabetes mellitusHypoglycemic medicationsOlder patientsVeterans Affairs national databasesIntensification of therapyRegular medical careObservational cohort studySingle clinic visitVA Medical CenterInfluence of ageClinic visitsCohort studyYounger patientsMedical therapyPharmacological therapyMedical CenterComorbiditiesMedical carePatientsTherapyMedicationsNational databaseMellitusOverall rateVisits