2024
Rheumatoid arthritis and peripartum cardiovascular complications: focusing on non-traditional cardiovascular risk factors to improve maternal outcomes
Goldstein S, Lindley K. Rheumatoid arthritis and peripartum cardiovascular complications: focusing on non-traditional cardiovascular risk factors to improve maternal outcomes. European Heart Journal 2024, 45: 1537-1539. PMID: 38713839, DOI: 10.1093/eurheartj/ehae164.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsMaternal cardiovascular risk factorsPre-conception counsellingNon-traditional cardiovascular risk factorsCardio-obstetricsAdverse pregnancy outcomesRisk factorsPregnancy outcomesCardiovascular adverse outcomesAdverse outcomesMaternal outcomesRheumatoid arthritisMaternal cardiovascular complicationsCardiovascular complicationsCounselingOutcomesPregnancyRiskArthritisPracticeFactorsComplex Congenital Heart Disease in the Adult
Goldstein S, Krasuski R. Complex Congenital Heart Disease in the Adult. Annual Review Of Medicine 2024, 75: 493-512. PMID: 38285514, DOI: 10.1146/annurev-med-050922-052324.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseAdult congenital heart diseaseComplex congenital heart diseaseHeart diseaseSevere birth defectsStructural abnormalitiesBirth defectsComplex lesionsFrequent causeHigh riskImprove outcomesPediatric outcomesHeterogeneous groupPalliative interventionsCardiovascular systemDiseaseAdultsOutcomesComplications426 Brain natriuretic peptide testing and severe maternal morbidity in pregnancies affected by heart disease
Denoble A, Federspiel J, Goldstein S, Culhane J, Dysart K. 426 Brain natriuretic peptide testing and severe maternal morbidity in pregnancies affected by heart disease. American Journal Of Obstetrics And Gynecology 2024, 230: s235-s236. DOI: 10.1016/j.ajog.2023.11.452.Peer-Reviewed Original Research
2023
Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States
Craig A, Campbell A, Snow S, Spates T, Goldstein S, Denoble A, Meng M, Schroder J, Flores K, Agarwal R, Ward C, Federspiel J. Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States. JACC Heart Failure 2023, 11: 1666-1674. PMID: 37804312, PMCID: PMC10841668, DOI: 10.1016/j.jchf.2023.08.018.Peer-Reviewed Original ResearchNontransfusion severe maternal morbiditySevere maternal morbidityHT recipientsHeart transplantationPreterm birthDelivery hospitalizationsGreater oddsPregnancy outcomesRate of SMMNationwide Readmissions DatabaseOutcome of pregnancyHigher readmission ratesProportional hazards regressionHigh morbidity rateMaternal morbidityReadmission ratesHospital readmissionAdjusted analysisComorbid conditionsClinical comorbiditiesHazards regressionMorbidity rateHigh riskHT historyDays postpartumUtilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy
Goldstein S, Kennedy K, Friedman D, Al‐Khatib S, Wang A. Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy. Journal Of The American Heart Association 2023, 12: e029293. PMID: 37586066, PMCID: PMC10492935, DOI: 10.1161/jaha.122.029293.Peer-Reviewed Original ResearchConceptsNew York Heart Association classPrimary prevention implantable cardioverter-defibrillatorHistory of nonsustained ventricular tachycardiaImplantable cardioverter-defibrillatorImplantable cardioverter-defibrillator utilizationNonsustained ventricular tachycardiaHypertrophic cardiomyopathyAssociation classVentricular tachycardiaOlder patientsCardioverter-defibrillatorLeft ventricular ejection fractionRisk factorsNational Cardiovascular Data Registry ICD RegistryFactors associated with mortalityImplantable cardioverter-defibrillator implantationAssociated with postdischarge mortalityVentricular ejection fractionPrevalence of risk factorsSudden cardiac deathPostdischarge hospitalizationAssociated with hospitalizationCenters for MedicareEjection fractionICD RegistryAntihypertensives in Pregnancy
Denoble A, Goldstein S, Pettker C. Antihypertensives in Pregnancy. Obstetrics And Gynecology Clinics Of North America 2023, 50: 39-78. PMID: 36822710, DOI: 10.1016/j.ogc.2022.10.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSignificant maternal morbidityTreatment of hypertensionAmniotic fluid volumeHypertensive disordersMaternal morbidityPregnant patientsFetal growthCurrent guidelinesEfficacy dataAvailable safetyPregnancyAntihypertensivesFluid volumeClose supervisionHypertensionMorbidityPatientsPostpartumMortalityAvailable dataDiagnosis
2022
Prospective Observational Study of N-terminal Pro–Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy
Denoble A, Moyett J, Goldstein S, Ward CC, Truong T, Erkanli A, James A, Grotegut C. Prospective Observational Study of N-terminal Pro–Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy. American Journal Of Perinatology 2022, 40: 467-474. PMID: 35973801, PMCID: PMC10168705, DOI: 10.1055/a-1925-1532.Peer-Reviewed Original ResearchConceptsNT-proBNP levelsBody mass indexProspective observational studyObese patientsNonobese patientsNT-proBNPWeeks postpartumObservational studyN-terminal pro-brain natriuretic peptide levelsN-terminal pro-brain natriuretic peptidePro-brain natriuretic peptide levelsLinear mixed effects modelsLower NT-proBNP levelsHigher systolic blood pressurePro-brain natriuretic peptidePregnant peopleNatriuretic peptide levelsSignificant medical comorbiditiesTime pointsSystolic blood pressureMixed effects modelsEffects modelLogNT-proBNPPP elevationHypertensive disordersImpact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations
Denoble A, Goldstein S, Wein L, Grotegut C, Federspiel J. Impact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations. JACC Advances 2022, 1: 100157. PMID: 36684662, PMCID: PMC9851052, DOI: 10.1016/j.jacadv.2022.100157.Peer-Reviewed Original ResearchSevere maternal morbidityIschemic heart diseaseDelivery hospitalizationsComplex survey methodsCardiac diseaseCardiac diagnosisMaternal morbidityHeart diseasePre-existing ischaemic heart diseasePre-existing ischemic heart diseaseNontransfusion severe maternal morbidityWorld Health Organization classificationClass IAdverse pregnancy outcomesNationwide Readmissions DatabaseRelative risk regressionWorld Health Organization class IPregnancy outcomesPrimary outcomeRetrospective studyAdverse outcomesUnadjusted analysesOrganization classificationRisk regressionWorse outcomesHypertensive Disorders of Pregnancy and Heart Failure Risk.
Goldstein SA, Pagidipati NJ. Hypertensive Disorders of Pregnancy and Heart Failure Risk. Current Hypertension Reports 2022, 24: 205-213. PMID: 35347569, DOI: 10.1007/s11906-022-01189-2.Peer-Reviewed Original ResearchRisk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease
Goldstein S, Savu A, Islam S, Ward C, Krasuski R, Grotegut C, Newby L, Hornberger L, Windram J, Kaul P. Risk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease. JACC Advances 2022, 1: 100036. PMID: 38939317, PMCID: PMC11198567, DOI: 10.1016/j.jacadv.2022.100036.Peer-Reviewed Original ResearchCongenital heart diseaseAssociation of HDPRisk factorsAdverse eventsAdverse outcomesCongenital heart disease lesionsHypertensive disorders of pregnancyPresence of HDPGestational age infantsDisorders of pregnancyAssociated with HDPPrevalence of HDPAssociated with increased riskRetrospective cohort studyDisease backgroundAssociated with certain adverse outcomesDelivery admissionPreterm deliveryHypertensive disordersChronic hypertensionAge infantsLive birthsMaternal characteristicsDiabetes mellitusStrength of associationComparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk
Denoble AE, Goldstein SA, Wein LE, Grotegut CA, Federspiel JJ. Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk. American Heart Journal 2022, 250: 11-22. PMID: 35526569, PMCID: PMC9836743, DOI: 10.1016/j.ahj.2022.04.009.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityWorld Health Organization classificationDelivery hospitalizationsCardiac diagnosisMaternal morbidityOrganization classificationMaternal cardiovascular riskNationwide Readmissions DatabaseRisk of deathSevere cardiac diseaseWeighted national estimateMWHO classificationDelivery admissionCardiovascular riskPregnant patientsSecondary outcomesPrimary outcomeRetrospective studyYear postpartumPregnancy counselingPrimary exposureMonths postpartumNationwide databaseCardiac diseaseElevated riskPulmonary Hypertension in Adults with Congenital Heart Disease
Goldstein S, Krasuski R. Pulmonary Hypertension in Adults with Congenital Heart Disease. Cardiology Clinics 2022, 40: 55-67. PMID: 34809917, DOI: 10.1016/j.ccl.2021.08.006.Peer-Reviewed Original ResearchConceptsPAH-CHDPulmonary arterial hypertension related to congenital heart diseaseSystemic-to-pulmonary shuntAssociated with significant morbidityCongenital heart diseasePulmonary vascular resistancePulmonary vascular remodelingShunt reversalEisenmenger syndromePulmonary hypertensionCentral cyanosisPrimary management strategySignificant morbidityMedical therapySevere elevationVascular resistanceDefect closureSevere phenotypeVascular remodelingHeart diseasePathological processesShuntCyanosisAdultsHypoxemiaRisk Factors and Outcomes Associated with Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease
Goldstein SA, Savu A, Islam S, Ward CC, Krasuski RA, Grotegut CA, Newby LK, Hornberger LK, Windram J, Kaul P. Risk factors and outcomes associated with hypertensive disorders of pregnancy in maternal congenital heart disease. JACC: Advances. 2022 Jun 1;1(2):100036.Peer-Reviewed Original ResearchImpact of chronic ischemic heart disease on severe maternal morbidity during delivery hospitalizations
Denoble A, Goldstein S, Grotegut C, Federspiel J. Impact of chronic ischemic heart disease on severe maternal morbidity during delivery hospitalizations. American Journal Of Obstetrics And Gynecology 2022, 226: s77. DOI: 10.1016/j.ajog.2021.11.146.Peer-Reviewed Original ResearchImpact of mechanical versus bioprosthetic heart valve on severe maternal morbidity during delivery hospitalizations
Denoble A, Federspiel J, Goldstein S, Grotegut C. Impact of mechanical versus bioprosthetic heart valve on severe maternal morbidity during delivery hospitalizations. American Journal Of Obstetrics And Gynecology 2022, 226: s469-s470. DOI: 10.1016/j.ajog.2021.11.778.Peer-Reviewed Original ResearchInstituting a Curriculum for Cardio-Obstetrics Subspecialty Fellowship Training.
Minhas AS, Goldstein SA, Vaught AJ, Lewey J, Ward C, Schulman SP, Michos ED. Instituting a Curriculum for Cardio-Obstetrics Subspecialty Fellowship Training. Methodist DeBakey Cardiovascular Journal 2022, 18: 14-23. PMID: 35734150, PMCID: PMC9165665, DOI: 10.14797/mdcvj.1101.Peer-Reviewed Original Research
2021
Peripartum Cardiomyopathy.
Farrell AS, Kuller JA, Goldstein SA, Dotters-Katz SK. Peripartum Cardiomyopathy. Obstetrical & Gynecological Survey 2021, 76: 485-492. PMID: 34449851, DOI: 10.1097/OGX.0000000000000903.Peer-Reviewed Original ResearchIMPACT OF CARDIOVASCULAR COMORBIDITY ON CONGENITAL HEART DISEASE DEATHS
Pinsker B, Shahid I, Kumar P, Krasuski M, Goldstein S, Serfas J, Khan M, Krasuski R. IMPACT OF CARDIOVASCULAR COMORBIDITY ON CONGENITAL HEART DISEASE DEATHS. Journal Of The American College Of Cardiology 2021, 77: 507. DOI: 10.1016/s0735-1097(21)01866-0.Peer-Reviewed Original ResearchRACIAL AND ETHNIC DISPARITIES IN LOCATION OF DEATH AMONG ADULT CONGENITAL HEART DISEASE PATIENTS
Serfas J, Kumar P, Shahid I, Goldstein S, Krasuski M, Khan M, Krasuski R. RACIAL AND ETHNIC DISPARITIES IN LOCATION OF DEATH AMONG ADULT CONGENITAL HEART DISEASE PATIENTS. Journal Of The American College Of Cardiology 2021, 77: 484. DOI: 10.1016/s0735-1097(21)01843-x.Peer-Reviewed Original ResearchAGE AND LOCATION OF DEATH DIFFER IN ADULT PATIENTS WITH CONGENITAL HEART DISEASE COMPARED WITH THE GENERAL POPULATION
Goldstein S, Kumar P, Shahid I, Serfas J, Krasuski M, Khan M, Krasuski R. AGE AND LOCATION OF DEATH DIFFER IN ADULT PATIENTS WITH CONGENITAL HEART DISEASE COMPARED WITH THE GENERAL POPULATION. Journal Of The American College Of Cardiology 2021, 77: 489. DOI: 10.1016/s0735-1097(21)01848-9.Peer-Reviewed Original Research