2023
Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy
Goldstein S, Kennedy K, Friedman D, Al‐Khatib S, Wang A. Utilization and Outcomes of Primary Prevention Implantable Cardioverter‐Defibrillators in Patients With Hypertrophic Cardiomyopathy. Journal Of The American Heart Association 2023, 12: e029293. PMID: 37586066, PMCID: PMC10492935, DOI: 10.1161/jaha.122.029293.Peer-Reviewed Original ResearchConceptsNew York Heart Association classPrimary prevention implantable cardioverter-defibrillatorHistory of nonsustained ventricular tachycardiaImplantable cardioverter-defibrillatorImplantable cardioverter-defibrillator utilizationNonsustained ventricular tachycardiaHypertrophic cardiomyopathyAssociation classVentricular tachycardiaOlder patientsCardioverter-defibrillatorLeft ventricular ejection fractionRisk factorsNational Cardiovascular Data Registry ICD RegistryFactors associated with mortalityImplantable cardioverter-defibrillator implantationAssociated with postdischarge mortalityVentricular ejection fractionPrevalence of risk factorsSudden cardiac deathPostdischarge hospitalizationAssociated with hospitalizationCenters for MedicareEjection fractionICD Registry
2016
Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non–ST-Segment–Elevation Acute Coronary Syndromes Clinical Trials
Kragholm K, Goldstein S, Yang Q, Lopes R, Schulte P, Bernacki G, White H, Mahaffey K, Giugliano R, Armstrong P, Harrington R, Tricoci P, Van de Werf F, Alexander J, Alexander K, Newby L. Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non–ST-Segment–Elevation Acute Coronary Syndromes Clinical Trials. Circulation 2016, 133: 1560-1573. PMID: 26957532, PMCID: PMC4856566, DOI: 10.1161/circulationaha.115.017299.Peer-Reviewed Original ResearchConceptsIncrease evidence-based careEvidence-based careClinical characteristicsClinical trialsAcute coronary syndrome trialsTranslation of clinical trialNon-ST segment elevation acute coronary syndromeNon-ST segment elevationPhase III clinical trialsPost-myocardial infarction mortalityIII clinical trialsClinical trial enrollmentInfarction mortalityAcute coronary syndromeClinical trial populationsAge strataGeneral populationTrial enrollmentIn-hospitalCoronary syndromeOlder patientsIncreased comorbiditiesTrial backgroundTrial populationEnrollment