2020
Sex differences in left ventricular electrical dyssynchrony and outcomes with cardiac resynchronization therapy
Friedman D, Emerek K, Sørensen P, Zeitler E, Goldstein S, Al-Khatib S, Søgaard P, Graff C, Atwater B. Sex differences in left ventricular electrical dyssynchrony and outcomes with cardiac resynchronization therapy. Heart Rhythm O2 2020, 1: 243-249. PMID: 34113878, PMCID: PMC8183970, DOI: 10.1016/j.hroo.2020.07.004.Peer-Reviewed Original ResearchLeft bundle branch blockCardiac resynchronization therapyElectrical dyssynchronyQRS areaHigher burden of risk factorsLV assist device implantationAssociated with better long-term outcomesQRS characteristicsCardiac resynchronization therapy benefitsBurden of risk factorsCox regression analysisLong-term outcomesBundle branch blockAssist device implantationLV dyssynchronyCardiac transplantationResynchronization therapyBranch blockDevice implantationDyssynchronyFemale sexQRSdRisk factorsElectrophysiological explanationMorphological assessment
2017
Relationship Between Peak Troponin Values and Long‐Term Ischemic Events Among Medically Managed Patients With Acute Coronary Syndromes
Goldstein S, Newby L, Cyr D, Neely M, Lüscher T, Brown E, White H, Ohman E, Roe M, Hamm C. Relationship Between Peak Troponin Values and Long‐Term Ischemic Events Among Medically Managed Patients With Acute Coronary Syndromes. Journal Of The American Heart Association 2017, 6: e005334. PMID: 28400368, PMCID: PMC5533023, DOI: 10.1161/jaha.116.005334.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedBiomarkersChi-Square DistributionClopidogrelDouble-Blind MethodFemaleHumansKaplan-Meier EstimateLinear ModelsMaleMiddle AgedMultivariate AnalysisNon-ST Elevated Myocardial InfarctionPlatelet Aggregation InhibitorsPrasugrel HydrochlorideProportional Hazards ModelsRisk FactorsTiclopidineTime FactorsTreatment OutcomeTroponinUp-RegulationConceptsNon-ST-segment elevation ACS patientsLong-term ischemic eventsACS patientsDiabetes mellitus prevalenceTroponin levelsBody mass indexStatistically significant heterogeneityGRACE risk scoreHeterogeneity of treatment effectsIschemic eventsIndex ACS eventACS eventsNon-ST-segment elevation ACSMedically managed patientsComposite end pointLong-term outcomesMass indexTreatment effectsRisk scorePeak troponin valuesPercutaneous coronary interventionSignificant heterogeneityStatistically significant differenceManaging patientsPeak troponin