2009
Stress, workload, sexual well‐being and quality of life among physician residents in training
Sangi‐Haghpeykar H, Ambani D, Carson S. Stress, workload, sexual well‐being and quality of life among physician residents in training. International Journal Of Clinical Practice 2009, 63: 462-467. PMID: 19222631, DOI: 10.1111/j.1742-1241.2008.01845.x.Peer-Reviewed Original ResearchConceptsQuality of lifeSexual healthSexual dysfunctionMedical residentsNormal sexual functioningYears of residencySexual functioningPhysician residentsFemale residentsMale residentsSexual lifeMajority of residentsSexual activityHigh levelsFemale medical residentsDysfunctionMost domainsImpact of stressResidency programsHealthLevel of stressSignificant improvementResidencyQuestionnaireResidents
2005
Prevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos
Krotz S, McKenzie L, Cisneros P, Buster J, Amato P, Carson S. Prevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos. Fertility And Sterility 2005, 83: 1742-1744. PMID: 15950645, DOI: 10.1016/j.fertnstert.2004.11.078.Peer-Reviewed Original ResearchConceptsPremature LH surgeRegular menstrual cyclesFrozen embryo transferLH surgeEmbryo transferUrinary LHMenstrual cyclePregnancy rateNatural cycle frozen embryo transferFrozen-thawed embryo transferAssisted reproductive technology programRetrospective cohort studyReproductive technology programFrozen-thawed embryosCohort studyPregnancy outcomesMenstruating womenHormone surgePremature LHMAIN OUTCOMEMedical CollegePrivate medical collegeLHWomenRIA kitPreimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia
Simpson J, Carson S, Cisneros P. Preimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia. JNCI Monographs 2005, 2005: 87-90. PMID: 15784832, DOI: 10.1093/jncimonographs/lgi027.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiopsyBlastocystBlastomeresCord Blood Stem Cell TransplantationEmbryo TransferFemaleGenetic CounselingGenetic Diseases, InbornGenetic Predisposition to DiseaseGenotypeHLA AntigensHumansInfant, NewbornMaleNeoplasmsPregnancyPregnancy OutcomePreimplantation DiagnosisTruth DisclosureWillsConceptsAdenomatous polyposis coliPreimplantation genetic diagnosisMolecular basisGenetic diagnosisMendelian disordersMendelian formsPolyposis coliEmbryosVon Hippel-Lindau syndromeMore cellsLi-Fraumeni syndromeGametesGenesPolar body biopsyDNADays postconceptionColiTransfer of embryosBlastocystsTrophectoderm biopsyStem cell implantationBRCA1Specific HLA genotypesGenotypesCells
2004
Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF
McKenzie L, Pangas S, Carson S, Kovanci E, Cisneros P, Buster J, Amato P, Matzuk M. Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF. Human Reproduction 2004, 19: 2869-2874. PMID: 15471935, DOI: 10.1093/humrep/deh535.Peer-Reviewed Original ResearchAdultC-Reactive ProteinCyclooxygenase 2Embryo, MammalianFemaleFertilization in VitroGene ExpressionGlucuronosyltransferaseGranulosa CellsHumansHyaluronan SynthasesIntercellular Signaling Peptides and ProteinsMembrane ProteinsPredictive Value of TestsPregnancyPregnancy RateProstaglandin-Endoperoxide SynthasesROC CurveSerum Amyloid P-ComponentAppearance of uterine perforation by hysterosalpingography
McKenzie L, Kovanci E, Amato P, Buster J, Carson S. Appearance of uterine perforation by hysterosalpingography. Fertility And Sterility 2004, 82: 1428-1429. PMID: 15533371, DOI: 10.1016/j.fertnstert.2004.07.926.Peer-Reviewed Original ResearchAbsence of secretory endometrium after false-positive home urine luteinizing hormone testing
McGovern P, Myers E, Silva S, Coutifaris C, Carson S, Legro R, Schlaff W, Carr B, Steinkampf M, Giudice L, Leppert P, Diamond M, Network N. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertility And Sterility 2004, 82: 1273-1277. PMID: 15533341, DOI: 10.1016/j.fertnstert.2004.03.070.Peer-Reviewed Original ResearchConceptsProportion of casesEndometrial biopsyProliferative endometriumLH testingHealth/National InstituteReproductive Medicine NetworkEvaluation of infertilityRegular menstrual cyclesAdditional confirmatory testingMulticenter clinical trialLate luteal phaseNational InstituteFalse-positive testsInfertile womenHormone testingSecretory endometriumMenstrual cycleClinical trialsLH testLuteal phaseInfertile couplesMAIN OUTCOMEChild healthFertile volunteersClinical practiceHistological dating of timed endometrial biopsy tissue is not related to fertility status
Coutifaris C, Myers E, Guzick D, Diamond M, Carson S, Legro R, McGovern P, Schlaff W, Carr B, Steinkampf M, Silva S, Vogel D, Leppert P, Network N. Histological dating of timed endometrial biopsy tissue is not related to fertility status. Fertility And Sterility 2004, 82: 1264-1272. PMID: 15533340, DOI: 10.1016/j.fertnstert.2004.03.069.Peer-Reviewed Original ResearchConceptsLate luteal phaseHistological datingInfertile couplesPhase biopsiesLuteal phaseCycle dayDaily urinary LH testingReproductive Medicine NetworkUrinary LH testingProspective multicenter studyRegular menstrual cyclesRecurrent pregnancy lossHistory of infertilityEndometrial biopsy tissueLogistic regression modelsInfertile womenInfertility practiceLH surgeMulticenter studyRegular intercourseBiopsy resultsPregnancy lossMenstrual cycleInclusion criteriaLive birthsPregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia
McKenzie L, Kovanci E, Amato P, Cisneros P, Lamb D, Carson S. Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia. Fertility And Sterility 2004, 82: 847-849. PMID: 15482758, DOI: 10.1016/j.fertnstert.2004.03.054.Peer-Reviewed Original ResearchConceptsIntracytoplasmic sperm injectionIVF/intracytoplasmic sperm injectionPregnancy outcomesSperm injectionFertilization/intracytoplasmic sperm injectionIVF/ICSI cyclesTertiary care centerAppropriate developmental milestonesBirth defectsStrict criteriaTime of deliveryKruger's strict criteriaYears of ageAcceptable pregnancy ratesOvarian stimulationICSI cyclesIncreased riskCare centerPregnancy rateRetrospective analysisMAIN OUTCOMETransvaginal aspirationEmbryo transferInfant statusSmall seriesNuclear chromosomal localization in human preimplantation embryos: correlation with aneuploidy and embryo morphology
McKenzie L, Carson S, Marcelli S, Rooney E, Cisneros P, Torskey S, Buster J, Simpson J, Bischoff F. Nuclear chromosomal localization in human preimplantation embryos: correlation with aneuploidy and embryo morphology. Human Reproduction 2004, 19: 2231-2237. PMID: 15298970, DOI: 10.1093/humrep/deh391.Peer-Reviewed Original ResearchConceptsChromosome 13Aneuploid blastomeresOrganization of chromosomesLocalization of chromosomesRegulatory protein functionHuman preimplantation embryosChromosome localizationChromosomal localizationProtein functionTranscriptional activityPreimplantation embryosChromosomesStage embryosEmbryo morphologyNormal blastomeresBlastomeresEmbryosHuman blastomeresSitu hybridizationSpatial organizationAbnormal embryosPreimplantation genetic diagnosisLocalizationGenetic diagnosisPaternal gonadal mosaicism detected in a couple with recurrent abortions undergoing PGD: FISH analysis of sperm nuclei proves valuable
Somprasit C, Aguinaga M, Cisneros P, Torsky S, Carson S, Buster J, Amato P, McAdoo S, Simpson J, Bischoff F. Paternal gonadal mosaicism detected in a couple with recurrent abortions undergoing PGD: FISH analysis of sperm nuclei proves valuable. Reproductive BioMedicine Online 2004, 9: 225-230. PMID: 15333256, DOI: 10.1016/s1472-6483(10)62134-7.Peer-Reviewed Original ResearchConceptsPaternal gonadal mosaicismSpontaneous abortionPreimplantation genetic diagnosisIVF-PGD cyclesRecurrent spontaneous abortionGonadal mosaicismIVF cyclesPaternal germ cellsPeripheral bloodRecurrent abortionCase reportPGD cyclesNormal karyotypeFemale partnersAbortionGenetic diagnosisIVFCytogenetic studiesDown syndrome critical regionGerm cellsUnexpected findingSitu hybridizationNormal embryosMosaicism
2002
Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome
Heard M, Pierce A, Carson S, Buster J. Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome. Fertility And Sterility 2002, 77: 669-673. PMID: 11937113, DOI: 10.1016/s0015-0282(01)03266-6.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeOvary syndromeSpontaneous abortionDiagnosis of PCOSAnovulatory infertility patientsUse of metforminResumption of mensesGastrointestinal-related side effectsEvidence of ovulationDosage of metforminAnovulatory patientsMetformin therapyPCOS resultsClomiphene citrateOvulation inductionPregnancy outcomesSpontaneous mensesInfertility patientsCase seriesMedian timeOvulatory responseMAIN OUTCOMESide effectsPatientsMetformin
2001
Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men
Guzick D, Overstreet J, Factor-Litvak P, Brazil C, Nakajima S, Coutifaris C, Carson S, Cisneros P, Steinkampf M, Hill J, Xu D, Vogel D. Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men. New England Journal Of Medicine 2001, 345: 1388-1393. PMID: 11794171, DOI: 10.1056/nejmoa003005.Peer-Reviewed Original ResearchMultiple pregnancies: action is taking place
Soules M, Chang R, Lipshultz L, Keye W, Carson S. Multiple pregnancies: action is taking place. Fertility And Sterility 2001, 75: 15-16. PMID: 11163809, DOI: 10.1016/s0015-0282(00)01726-x.Commentaries, Editorials and Letters
2000
Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series
Casson P, Lindsay M, Pisarska M, Carson S, Buster J. Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series. Human Reproduction 2000, 15: 2129-2132. PMID: 11006185, DOI: 10.1093/humrep/15.10.2129.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotrophinOvarian stimulationDHEA treatmentPoor respondersPoor responseInsulin-like growth factor-1 effectsGrowth hormonePg/Healthy non-smoking womenDay 3 FSHOvarian stimulation responseOvarian stimulation cyclesNon-smoking womenPeak oestradiol concentrationsGonadotrophin doseDehydroepiandrosterone administrationGonadotrophin administrationOvarian responseCase seriesTwin pregnanciesMIU/Intrauterine inseminationOestradiol concentrationsFollicular maturityChorionic gonadotrophin
1999
Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick D, Carson S, Coutifaris C, Overstreet J, Factor-Litvak P, Steinkampf M, Hill J, Mastroianni L, Buster J, Nakajima S, Vogel D, Canfield R. Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility. New England Journal Of Medicine 1999, 340: 177-183. PMID: 9895397, DOI: 10.1056/nejm199901213400302.Peer-Reviewed Original ResearchConceptsIntrauterine insemination groupIntrauterine inseminationInduction of superovulationIntracervical inseminationCox proportional hazards analysisProportional hazards analysisTreatment of infertilityInfertility factorsClinical trialsInfertile couplesEfficacy of superovulationPregnancySuperovulationTreatmentInfertilityHigh rateMotile spermInseminationGroupInductionGonadotropinTrialsWomen
1998
Heterotopic abdominal pregnancy treated at laparoscopy
Pisarska M, Casson P, Moise K, DiMaio D, Buster J, Carson S. Heterotopic abdominal pregnancy treated at laparoscopy. Fertility And Sterility 1998, 70: 159-160. PMID: 9660440, DOI: 10.1016/s0015-0282(98)00104-6.Peer-Reviewed Original ResearchConceptsHeterotopic abdominal pregnancyAbdominal pregnancyIVF-ETConcurrent intrauterine pregnancyIntrauterine pregnancyLaparoscopic treatmentHuman chorionic gonadotropin levelsEctopic abdominal pregnancyPrimary abdominal pregnancyPelvic ultrasound examinationChorionic gonadotropin levelsSuccessful laparoscopic treatmentAbdominal gestationLuteal supportIntrauterine gestationOvulation inductionGonadotropin levelsPathologic findingsIVF programCase reportUltrasound examinationEarly diagnosisMAIN OUTCOMEPregnancyLaparoscopyTestosterone Delivery Systems for Women: Present Status and Future Promise
Casson P, Carson S, Buster J. Testosterone Delivery Systems for Women: Present Status and Future Promise. Seminars In Reproductive Medicine 1998, 16: 153-159. PMID: 9711681, DOI: 10.1055/s-2007-1016266.Peer-Reviewed Original ResearchConceptsAndrogen replacement modalitiesTestosterone delivery systemsSurgical menopauseHormone replacementMale hypogonadismMenopausal womenReplacement modalityPhysiologic deliveryNon-reproductive effectsAndrogen levelsT replacementNew delivery systemDelivery systemWomenModalitiesHypogonadismMenopausePatientsReplacementFuture promiseTherapyTestosteroneSteroidsLack of Association Between Antiphospholipid Antibodies and First-Trimester Spontaneous Abortion: Prospective Study of Pregnancies Detected Within 21 Days of Conception 11Supported by grants and contracts from the National Institute of Child Health and Human Development, National Institutes of Health.
Simpson J, Carson S, Chesney C, Conley M, Metzger B, Aarons J, Holmes L, Jovanovic-Peterson L, Knopp R, Mills J. Lack of Association Between Antiphospholipid Antibodies and First-Trimester Spontaneous Abortion: Prospective Study of Pregnancies Detected Within 21 Days of Conception 11Supported by grants and contracts from the National Institute of Child Health and Human Development, National Institutes of Health. Fertility And Sterility 1998, 69: 814-820. PMID: 9591485, DOI: 10.1016/s0015-0282(98)00054-5.Peer-Reviewed Original ResearchConceptsAntiphospholipid antibodiesAnticardiolipin antibodiesPregnancy lossProspective studyFirst trimester pregnancy lossEnzyme immunoassayFirst-trimester spontaneous abortionsFirst trimester lossNational InstituteLack of associationDay of conceptionFetal deathRetrospective studySpontaneous abortionLive birthsMAIN OUTCOMEChild healthSuch antibodiesBlood samplesPregnancyMulticenter universityAntibodiesSerumWomenSelection bias
1997
Effect of sexual abstinence on the proportion of X-bearing sperm as assessed by multicolor fluorescent in situ hybridization
Hilsenrath R, Swarup M, Bischoff F, Buster J, Carson S. Effect of sexual abstinence on the proportion of X-bearing sperm as assessed by multicolor fluorescent in situ hybridization. Fertility And Sterility 1997, 68: 510-513. PMID: 9314924, DOI: 10.1016/s0015-0282(97)00247-1.Peer-Reviewed Original Research
1996
Prospective study showing that antisperm antibodies are not associated with pregnancy losses**Supported by a contract with the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Simpson J, Carson S, Mills J, Conley M, Aarons J, Holmes L, Jovanovic-Peterson L, Knopp R, Metzger B. Prospective study showing that antisperm antibodies are not associated with pregnancy losses**Supported by a contract with the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland. Fertility And Sterility 1996, 66: 36-42. PMID: 8752608, DOI: 10.1016/s0015-0282(16)58384-8.Peer-Reviewed Original ResearchConceptsIgM antisperm antibodiesAntisperm antibodiesPregnancy lossIgA antisperm antibodiesNondiabetic womenPregnancy outcomesPositive findingsFirst trimester pregnancy lossTrimester pregnancy lossFirst-trimester serumIndirect immunobead testNational InstituteOnly positive findingDay of conceptionMaternal serumClinical statusProspective studyImmunobead testLiveborn infantsProspective dataChild healthPositive testIgM bindingRegional bindingLocation of antibody