Quantitative DNA perturbations of p53 in endometriosis: analysis of American and Icelandic cases
Gylfason J, Dang D, Petursdottir V, Benediktsdottir K, Geirsson R, Poindexter A, Mitchell-Leef D, Buster J, Carson S, Simpson J, Bischoff F. Quantitative DNA perturbations of p53 in endometriosis: analysis of American and Icelandic cases. Fertility And Sterility 2005, 84: 1388-1394. PMID: 16275233, DOI: 10.1016/j.fertnstert.2005.05.031.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionUnaffected controlsSevere stage endometriosisReal-time polymerase chain reactionFresh surgical tissuesSevere endometriosisEndometriotic tissueMAIN OUTCOMEQuantitative aberrationsControl bloodSurgical tissuesP53 valuesTissue specimensLocus alterationsEndometriosisP53 lossP53 gainChain reactionSignificant differencesGAPDH controlTissueP53Copy numberAmerican subjects