2012
Endometrial Shedding Effect on Conception and Live Birth in Women With Polycystic Ovary Syndrome
Diamond M, Kruger M, Santoro N, Zhang H, Casson P, Schlaff W, Coutifaris C, Brzyski R, Christman G, Carr B, McGovern P, Cataldo N, Steinkampf M, Gosman G, Nestler J, Carson S, Myers E, Eisenberg E, Legro R. Endometrial Shedding Effect on Conception and Live Birth in Women With Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2012, 67: 548-549. DOI: 10.1097/01.ogx.0000421452.19985.8f.Peer-Reviewed Original ResearchPolycystic ovary syndromeLive birth rateProgestin withdrawalEndometrial sheddingLive birthsAnovulatory womenClomiphene citrateOvary syndromeOvulation inductionSpontaneous mensesProgestin-induced withdrawal bleedingEunice Kennedy Shriver National InstituteBirth rateAdministration of clomipheneOligo-ovulatory womenPrevious bleeding episodesDouble-blind trialFirst-line therapyCommon clinical practiceUse of progestinsOccurrence of ovulationRate of conceptionWithdrawal bleedWithdrawal bleedingBleeding episodes
2010
Predictors of Pregnancy in Women With Polycystic Ovary Syndrome
Rausch M, Legro R, Barnhart H, Schlaff W, Carr B, Diamond M, Carson S, Steinkampf M, McGovern P, Cataldo N, Gosman G, Nestler J, Giudice L, Leppert P, Myers E, Coutifaris C. Predictors of Pregnancy in Women With Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2010, 65: 30-32. DOI: 10.1097/01.ogx.0000367515.48912.b1.Peer-Reviewed Original ResearchPolycystic ovary syndromeClomiphene citrateLive birthsOvary syndromeTreatment successCurrent first-line treatmentSelective estrogen receptor modulatorsBaseline patient characteristicsFirst-line treatmentFree androgen indexPredictors of pregnancyPrior pregnancy lossPrimary study outcomeBody mass indexInsulin sensitizer metforminEstrogen receptor modulatorsRelevant prognostic modelHirsutism scoreAndrogen indexGlucose intoleranceOvulation inductionPatient characteristicsPregnancy outcomesSmoking historyInfertile women
2007
Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome
Legro R, Barnhart H, Schlaff W, Carr B, Diamond M, Carson S, Steinkampf M, Coutifaris C, McGovern P, Cataldo N, Gosman G, Nestler J, Giudice L, Leppert P, Myers E. Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2007, 62: 386-388. DOI: 10.1097/01.ogx.0000265909.61668.01.Peer-Reviewed Original ResearchPolycystic ovary syndromeExtended-release metforminMetformin groupLive birthsTreatment groupsClomiphene citrateOvary syndromeInfertile womenPregnancy lossSex hormone-binding globulin levelsAbstract Polycystic ovary syndromeHormone-binding globulin levelsFirst trimester pregnancy lossClomiphene-treated patientsDose of clomipheneMetformin-treated womenPlacebo-controlled trialSerious adverse eventsFirst-line treatmentFree androgen indexLive birth rateGastrointestinal side effectsBody mass indexEarly pregnancy lossSingle drug group
2002
Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome
Heard M, Pierce A, Carson S, Buster J. Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome. Fertility And Sterility 2002, 77: 669-673. PMID: 11937113, DOI: 10.1016/s0015-0282(01)03266-6.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeOvary syndromeSpontaneous abortionDiagnosis of PCOSAnovulatory infertility patientsUse of metforminResumption of mensesGastrointestinal-related side effectsEvidence of ovulationDosage of metforminAnovulatory patientsMetformin therapyPCOS resultsClomiphene citrateOvulation inductionPregnancy outcomesSpontaneous mensesInfertility patientsCase seriesMedian timeOvulatory responseMAIN OUTCOMESide effectsPatientsMetformin