Doxorubicin-Conjugated Bimetallic Silver–Gadolinium Nanoalloy for Multimodal MRI-CT-Optical Imaging and pH-Responsive Drug Release
Mishra S, Kannan S. Doxorubicin-Conjugated Bimetallic Silver–Gadolinium Nanoalloy for Multimodal MRI-CT-Optical Imaging and pH-Responsive Drug Release. ACS Biomaterials Science & Engineering 2017, 3: 3607-3619. PMID: 33445395, DOI: 10.1021/acsbiomaterials.7b00498.Peer-Reviewed Original ResearchBimetallic nanoparticlesMicrowave-assisted polyol synthesisPH-sensitive hydrazone linkageDrug releaseResponsive drug releaseNegligible drug releaseOne-pot synthesisBimetallic silverCancer theranosisContrast abilityCapping agentPolyol synthesisAverage sizeHydrazone linkagePotential anticancer drugsAcidic mediumContrast performanceOptical imagingParamagnetic behaviorPhysiological pHMolar ratioChitosanAnticancer drugsAgDOX