2021
Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates
Fuery MA, Chouairi F, Natov P, Bhinder J, Rose Chiravuri M, Wilson L, Clark KA, Reinhardt SW, Mullan C, Miller PE, Davis RP, Rogers JG, Patel CB, Sen S, Geirsson A, Anwer M, Desai N, Ahmad T. Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates. Journal Of The American Heart Association 2021, 10: e023662. PMID: 34743559, PMCID: PMC9075266, DOI: 10.1161/jaha.121.023662.Peer-Reviewed Original ResearchMeSH KeywordsDatabases, FactualFemaleHeart TransplantationHumansMaleRetrospective StudiesSurvival AnalysisTissue DonorsTreatment OutcomeWaiting ListsConceptsLow-urgency patientsHigh-urgency patientsUrgency patientsCardiac transplantationAllocation system changeLonger waitlist timesOrgan Sharing databaseTime of transplantationCardiac transplantation candidatesNew allocation systemBaseline recipientPosttransplantation outcomesPosttransplantation survivalAdditional comorbiditiesClinical characteristicsConclusions PatientsHepatitis CIschemic timeTransplantation candidatesSharing databaseWaitlist timeWaitlist survivalUnited NetworkRetrospective analysisPatientsMechanical ventilation at the time of heart transplantation and associations with clinical outcomes
Miller PE, Mullan CW, Chouairi F, Sen S, Clark KA, Reinhardt S, Fuery M, Anwer M, Geirsson A, Formica R, Rogers JG, Desai NR, Ahmad T. Mechanical ventilation at the time of heart transplantation and associations with clinical outcomes. European Heart Journal Acute Cardiovascular Care 2021, 10: 843-851. PMID: 34389855, PMCID: PMC8557439, DOI: 10.1093/ehjacc/zuab063.Peer-Reviewed Original ResearchMeSH KeywordsAdultDatabases, FactualHeart TransplantationHumansLogistic ModelsOdds RatioRespiration, ArtificialRetrospective StudiesConceptsHeart transplantationMechanical ventilationSingle-organ heart transplantationMedian waitlist timeOrgan Sharing databaseTime of transplantationMultivariable logistic regressionMultivariable adjustmentWaitlist timeClinical outcomesSharing databasePoor outcomeVentilated patientsUnited NetworkTemporary mechanical supportClinical acuityTransplantationPatientsPrevious dialysisLogistic regressionMortalityStrong associationReasonable outcomesOutcomesAssociationChanges in Use of Left Ventricular Assist Devices as Bridge to Transplantation With New Heart Allocation Policy
Mullan CW, Chouairi F, Sen S, Mori M, Clark KAA, Reinhardt SW, Miller PE, Fuery MA, Jacoby D, Maulion C, Anwer M, Geirsson A, Mulligan D, Formica R, Rogers JG, Desai NR, Ahmad T. Changes in Use of Left Ventricular Assist Devices as Bridge to Transplantation With New Heart Allocation Policy. JACC Heart Failure 2021, 9: 420-429. PMID: 33714748, DOI: 10.1016/j.jchf.2021.01.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultHeart FailureHeart TransplantationHeart-Assist DevicesHumansPolicyRetrospective StudiesTissue DonorsTreatment OutcomeUnited StatesWaiting ListsConceptsDonor heart allocation systemNumber of patientsHeart allocation systemVentricular assist deviceWaitlist survivalAssist deviceNew heart allocation policyLeft ventricular assist deviceAllocation system changePost-transplant mortalityOrgan Sharing databaseOutcomes of patientsPost-transplantation outcomesProportion of patientsTime of transplantContinuous-flow LVADPost-transplantation survivalHeart allocation policyNew allocation systemBaseline recipientStatus 1AHeart transplantationIschemic timeLVAD implantationTransplant list
2020
Sex Differences in Patients Receiving Left Ventricular Assist Devices for End-Stage Heart Failure
Gruen J, Caraballo C, Miller PE, McCullough M, Mezzacappa C, Ravindra N, Mullan CW, Reinhardt SW, Mori M, Velazquez E, Geirsson A, Ahmad T, Desai NR. Sex Differences in Patients Receiving Left Ventricular Assist Devices for End-Stage Heart Failure. JACC Heart Failure 2020, 8: 770-779. PMID: 32653446, DOI: 10.1016/j.jchf.2020.04.015.Peer-Reviewed Original ResearchMeSH KeywordsAgedFemaleHeart FailureHeart TransplantationHeart-Assist DevicesHumansMaleRegistriesRetrospective StudiesSex CharacteristicsTreatment OutcomeConceptsAdverse eventsVentricular assist deviceClinical outcomesPotential underuseHigh riskAssist deviceEnd-stage heartWomen 65 yearsRisk of deathContinuous-flow LVADYears of ageAdvanced treatment optionsSex differencesHeart transplantationMultivariable adjustmentHeart failureHeart transplantSimilar incidenceTreatment optionsSimilar riskSurvival analysisLVADPatientsDevice malfunctionWomen