2022
Comfort Measures Only in Myocardial Infarction: Prevalence of This Status, Change Over Time, and Predictors From a Nationwide Study
Haghighat L, Reinhardt SW, Saly DL, Lu D, Matsouaka RA, Wang TY, Desai NR. Comfort Measures Only in Myocardial Infarction: Prevalence of This Status, Change Over Time, and Predictors From a Nationwide Study. Circulation Cardiovascular Quality And Outcomes 2022, 15: e007610. PMID: 35041476, DOI: 10.1161/circoutcomes.120.007610.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionChest Pain-MI RegistryACTION Registry-GWTGHospital major bleedingIndependent patient characteristicsRetrospective cohort studyHigh-risk patientsMortality risk scoreAggressive initial managementHigh mortality rateMedian odds ratioCMO patientsHospital complicationsMajor bleedingCardiogenic shockCohort studyDiagnostic catheterizationMost patientsNonprivate insurancePatient characteristicsInitial managementProcedural complicationsSuch patientsMale gender
2021
Personalizing the decision of dabigatran versus warfarin in atrial fibrillation: A secondary analysis of the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) trial
Reinhardt SW, Desai NR, Tang Y, Jones PG, Ader J, Spertus JA. Personalizing the decision of dabigatran versus warfarin in atrial fibrillation: A secondary analysis of the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) trial. PLOS ONE 2021, 16: e0256338. PMID: 34411158, PMCID: PMC8376053, DOI: 10.1371/journal.pone.0256338.Peer-Reviewed Original ResearchConceptsAbsolute risk reductionPrior stroke/TIAStroke/TIASystemic embolismAtrial fibrillationMajor bleedingRE-LYOlder patientsLong-Term Anticoagulation Therapy (RE-LY) trialStroke/systemic embolismGood renal functionHigh-risk patientsHistory of diabetesRE-LY trialPatient-level dataShared decision makingMedian followRenal functionHeart failureHeavier patientsMultivariable modelDabigatranIndividual patientsTreatment groupsIndividualized estimates
2019
Clinical Implications of Respiratory Failure in Patients Receiving Durable Left Ventricular Assist Devices for End-Stage Heart Failure
Miller PE, Caraballo C, Ravindra NG, Mezzacappa C, McCullough M, Gruen J, Levin A, Reinhardt S, Ali A, Desai NR, Ahmad T. Clinical Implications of Respiratory Failure in Patients Receiving Durable Left Ventricular Assist Devices for End-Stage Heart Failure. Circulation Heart Failure 2019, 12: e006369. PMID: 31707800, DOI: 10.1161/circheartfailure.119.006369.Peer-Reviewed Original ResearchMeSH KeywordsAgedDisease ProgressionFemaleFrailtyHealth StatusHeart FailureHeart-Assist DevicesHumansIntubation, IntratrachealLungMaleMiddle AgedProsthesis DesignQuality of LifeRecovery of FunctionRegistriesRespiratory InsufficiencyRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVentricular Function, LeftConceptsMechanically Assisted Circulatory Support profile 1 patientsVentricular assist device implantationProfile 1 patientsAssist device implantationRespiratory failureInteragency RegistryLVAD implantationCirculatory supportDevice implantationMechanically Assisted Circulatory Support profile 1Right ventricular assist device implantationLeft ventricular assist device implantationAdvanced heart failure patientsEnd-stage heart failureMechanically Assisted Circulatory SupportAdvanced heart failure populationHeart failure populationHeart failure patientsLandmark clinical trialsMechanical circulatory supportContinuous-flow LVADVentricular assist devicePostimplant complicationsFailure patientsLVAD placement
2018
Late Presentation and Missed Opportunities for HIV Diagnosis in Guatemala
Meléndez J, Reinhardt SW, O’Halloran J, Spec A, Alonzo Cordon A, Powderly WG, Mejia Villatoro C. Late Presentation and Missed Opportunities for HIV Diagnosis in Guatemala. AIDS And Behavior 2018, 23: 920-928. PMID: 30426264, PMCID: PMC7397713, DOI: 10.1007/s10461-018-2331-y.Peer-Reviewed Original ResearchConceptsLate presentersHIV diagnosisLarge tertiary referral centerEarly HIV diagnosisRetrospective cohort studyProportion of patientsTertiary referral centerTraditional healthcare settingsMissed opportunityCohort studyReferral centerLate presentationOutpatient careHealthcare settingsPatientsDiagnosisYear rateHigh rateCareRural dwellersMorbidityHIVMortalityProportionAIDS