2022
CT angiographic radiomics signature for risk stratification in anterior large vessel occlusion stroke
Avery EW, Behland J, Mak A, Haider SP, Zeevi T, Sanelli PC, Filippi CG, Malhotra A, Matouk CC, Griessenauer CJ, Zand R, Hendrix P, Abedi V, Falcone GJ, Petersen N, Sansing LH, Sheth KN, Payabvash S. CT angiographic radiomics signature for risk stratification in anterior large vessel occlusion stroke. NeuroImage Clinical 2022, 34: 103034. PMID: 35550243, PMCID: PMC9108990, DOI: 10.1016/j.nicl.2022.103034.Peer-Reviewed Original ResearchMeSH KeywordsArterial Occlusive DiseasesHumansRetrospective StudiesRisk AssessmentStrokeThrombectomyTomography, X-Ray ComputedTreatment OutcomeConceptsLarge vessel occlusion strokeIndependent cohortPrognostication toolsMechanical thrombectomyRisk stratificationOcclusion strokeExternal cohortAnterior circulation large vessel occlusion strokeOutcome predictionAcute stroke triageAnterior circulation territoryRadiomic featuresTime of admissionGeisinger Medical CenterLVO stroke patientsReliable clinical informationSignificant differencesAdmission CTAStroke patientsPrognostic informationFavorable outcomeStroke triageTreatment decisionsMedical CenterRadiomics signature
2021
Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population
Haider SP, Qureshi AI, Jain A, Tharmaseelan H, Berson ER, Zeevi T, Majidi S, Filippi CG, Iseke S, Gross M, Acosta JN, Malhotra A, Kim JA, Sansing LH, Falcone GJ, Sheth KN, Payabvash S. Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population. European Journal Of Neurology 2021, 28: 2989-3000. PMID: 34189814, PMCID: PMC8818333, DOI: 10.1111/ene.15000.Peer-Reviewed Original ResearchConceptsAdmission Glasgow Coma ScaleGlasgow Coma ScaleRadiomics signatureMRS scoreHematoma volumeICH volumeClinical severityNoncontrast head CT scansAdmission National InstitutesHealth Stroke ScaleRankin Scale scoreStrong associationBaseline clinical severityMedium-term outcomesIndependent validation cohortHead CT scanATACH-2 trialStroke ScaleAdmission NIHSSIndependent predictorsClinical presentationComa ScaleBaseline CTICH patientsValidation cohortEarly head CT in post-cardiac arrest patients: A helpful tool or contributor to self-fulfilling prophecy?
Beekman R, Maciel CB, Ormseth CH, Zhou SE, Galluzzo D, Miyares LC, Torres-Lopez VM, Payabvash S, Mak A, Greer DM, Gilmore EJ. Early head CT in post-cardiac arrest patients: A helpful tool or contributor to self-fulfilling prophecy? Resuscitation 2021, 165: 68-76. PMID: 34147572, DOI: 10.1016/j.resuscitation.2021.06.004.Peer-Reviewed Original ResearchMeSH KeywordsGray MatterHeart ArrestHumansPrognosisReproducibility of ResultsRetrospective StudiesTomography, X-Ray ComputedConceptsGray-white matter ratioHCT findingsArrest patientsInter-rater reliabilityPost-cardiac arrest patientsTertiary care academic medical centerEarly head CTPost-CA carePost-CA patientsCardiac arrest patientsHalf of casesAcademic medical centerElectronic medical recordsWithdrawal of lifeNeurophysiologic testingSpontaneous circulationInjury burdenMedical recordsHead CTTherapeutic decisionsMedical CenterPatientsNeurointensivistsHctTemperature management
2020
Choice of imaging modality for pre-treatment staging of head and neck cancer impacts TNM staging
Mur T, Sambhu KM, Mahajan A, Payabvash S, Fernandez J, Edwards HA. Choice of imaging modality for pre-treatment staging of head and neck cancer impacts TNM staging. American Journal Of Otolaryngology 2020, 41: 102662. PMID: 32858370, DOI: 10.1016/j.amjoto.2020.102662.Peer-Reviewed Original ResearchConceptsPET/CTLow-dose nonenhanced CTDistant metastasisChest CTNeck cancerNonenhanced CTF-fluorodeoxyglucose positron emission tomographyF-FDG PET/CTDiagnostic chest CTDistant metastatic diseaseInitiation of therapyRetrospective cohort studyPre-treatment stagingTertiary care settingSignificant differencesPositron emission tomographyMetastatic diseaseCohort studyOncologic treatmentTNM stagingInaccurate stagingNeck radiologistsCare settingsSingle patientPatients
2019
Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma.
Kann BH, Hicks DF, Payabvash S, Mahajan A, Du J, Gupta V, Park HS, Yu JB, Yarbrough WG, Burtness BA, Husain ZA, Aneja S. Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma. Journal Of Clinical Oncology 2019, 38: 1304-1311. PMID: 31815574, DOI: 10.1200/jco.19.02031.Peer-Reviewed Original ResearchConceptsNeck squamous cell carcinomaExtranodal extensionSquamous cell carcinomaLymph nodesCell carcinomaContrast-enhanced CT scanDiagnostic abilityBoard-certified neuroradiologistsTreatment escalationCancer Genome AtlasPathologic confirmationPretreatment identificationDiagnostic challengeExternal validation data setsPathology resultsPretreatment imagingPoor prognosticatorClinical utilityCT scanPatientsClinical decisionHNSCCDiagnostic accuracyInstitutional ValidationGenome Atlas
2017
Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis
Payabvash S, Taleb S, Qureshi AI. Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis. British Journal Of Radiology 2017, 90: 20160869. PMID: 28165757, PMCID: PMC5605076, DOI: 10.1259/bjr.20160869.Peer-Reviewed Original ResearchConceptsM1 segment occlusionDisability/deathSuccessful endovascular recanalizationVoxel-based analysisFinal infarct volumeSuccessful recanalizationSegment occlusionInfarct volumeFavorable outcomePrecentral gyrusCerebral regionsEndovascular recanalizationEndovascular treatmentInsular ribbonSmaller final infarct volumesDays post-symptom onsetMiddle cerebral artery M1 segmentModified Rankin Scale scoreCerebral Infarction scoreTimely reperfusion treatmentEarly clinical outcomesHigh ratePost-symptom onsetSmaller infarct volumesRankin Scale score
2016
Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke
Payabvash S, Noorbaloochi S, Qureshi AI. Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke. Journal Of Neuroimaging 2016, 27: 227-231. PMID: 27593522, DOI: 10.1111/jon.12383.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreDisability/deathAnterior circulation strokeAcute ischemic changesSymptomatic intracranial hemorrhageIntracranial hemorrhageIschemic changesIndependent predictorsFavorable outcomeIntravenous thrombolytic therapyCT/MRI scansRankin Scale scoreEarly ischemic changesAcute ischemic infarctTopographic assessmentIschemic infarctAdmission CTClinical outcomesStroke patientsThrombolytic therapyCT scoreLentiform nucleusTomography scanImproved outcomesPrognostic toolClinical implications of eye deviation on admission CT examination of acute ischaemic stroke patients
Payabvash S, Qureshi I, Qureshi AI. Clinical implications of eye deviation on admission CT examination of acute ischaemic stroke patients. Clinical Radiology 2016, 71: 1314.e11-1314.e15. PMID: 27592397, DOI: 10.1016/j.crad.2016.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAgedBrainEyeFemaleFixation, OcularHumansMaleMiddle AgedPredictive Value of TestsSeverity of Illness IndexStrokeTomography, X-Ray ComputedConceptsAlberta Stroke Program Early CT ScoreAcute ischemic stroke patientsIschemic stroke patientsHigher admission NIHSS scoresAdmission NIHSS scoreEye deviationStroke patientsNIHSS scoreHaemorrhagic transformationCT examinationsLow Alberta Stroke Program Early CT ScoreScale scoreHealth Stroke Scale scoreOlder ageAdmission CT examinationAdmission National InstitutesPatients' older ageStroke Scale scoreHigh rateRankin Scale scoreInfarct volumeMRS scoreAdmission CTCT scorePrognostic valueCT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location
Benson JC, Payabvash S, Mortazavi S, Zhang L, Salazar P, Hoffman B, Oswood M, McKinney AM. CT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location. American Journal Of Neuroradiology 2016, 37: 2239-2244. PMID: 27538902, PMCID: PMC7963880, DOI: 10.3174/ajnr.a4904.Peer-Reviewed Original ResearchClinical diffusion mismatch better discriminates infarct growth than mean transit time–diffusion weighted imaging mismatch in patients with middle cerebral artery–M1 occlusion and limited infarct core
Nogueira RG, Kemmling A, Souza LM, Payabvash S, Hirsch JA, Yoo AJ, Lev MH. Clinical diffusion mismatch better discriminates infarct growth than mean transit time–diffusion weighted imaging mismatch in patients with middle cerebral artery–M1 occlusion and limited infarct core. Journal Of NeuroInterventional Surgery 2016, 9: 127. PMID: 26957483, DOI: 10.1136/neurintsurg-2014-011602.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCerebral AngiographyCerebral InfarctionCerebrovascular CirculationDiffusion Magnetic Resonance ImagingDisease ProgressionFemaleHumansImage Processing, Computer-AssistedInfarction, Middle Cerebral ArteryMalePredictive Value of TestsRetrospective StudiesStrokeTomography, X-Ray ComputedConceptsClinical-diffusion mismatchMCA M1 occlusionAdmission Alberta Stroke Program Early CT scoreSmall infarct coreBaseline NIHSS scoreInfarct growthNIHSS scoreInfarct coreDiffusion mismatchDWI volumeStroke patientsAlberta Stroke Program Early CT ScoreMiddle cerebral artery M1 occlusionProximal middle cerebral artery occlusionMiddle cerebral artery occlusionMTT lesionsUni-/multivariate analysesBaseline National InstitutesHealth Stroke ScaleAdmission NIHSS scoreCerebral artery occlusionConsecutive stroke patientsOnly independent predictorDWI lesionsStroke Scale
2015
Bilateral persistent fetal vasculature due to a mutation in the Norrie disease protein gene
Payabvash S, Anderson JS, Nascene DR. Bilateral persistent fetal vasculature due to a mutation in the Norrie disease protein gene. The Neuroradiology Journal 2015, 28: 623-627. PMID: 26459204, PMCID: PMC4757132, DOI: 10.1177/1971400915609350.Peer-Reviewed Original ResearchMeSH KeywordsBlindnessEye ProteinsGenetic Diseases, X-LinkedHumansInfantMagnetic Resonance ImagingMaleMutationNerve Tissue ProteinsNervous System DiseasesOptic DiskPersistent Fetal Circulation SyndromeRetinal DegenerationRetinal DiseasesRetinal HemorrhageSpasms, InfantileTomography, X-Ray ComputedVitreous BodyDifferentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging
Payabvash S, Meric K, Cayci Z. Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging. Clinical Imaging 2015, 40: 101-105. PMID: 26454617, DOI: 10.1016/j.clinimag.2015.09.001.Peer-Reviewed Original ResearchMeSH KeywordsDiagnosis, DifferentialFemaleFluorodeoxyglucose F18Head and Neck NeoplasmsHumansImage-Guided BiopsyLymph NodesLymphatic DiseasesLymphatic MetastasisMaleMiddle AgedMultimodal ImagingNeckPositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesSensitivity and SpecificityTomography, X-Ray ComputedConceptsHead/neck cancerCervical lymph nodesMalignant cervical lymph nodesLymph nodesNeck cancerPositron emission tomographySUV maxHigh maximum standardized uptake valueBenign cervical lymph nodesMaximum standardized uptake valueLymph node biopsyMalignant lymph nodesMalignant cervical lymphadenopathyPET/CT imagingStandardized uptake valueSUV max valuesShort-axis diameterCervical lymphadenopathyNode biopsyMalignant lymphadenopathyRetrospective studyPatientsUptake valueEmission tomographyCancerDetection of Intraparenchymal Hemorrhage After Endovascular Therapy in Patients with Acute Ischemic Stroke Using Immediate Postprocedural Flat‐Panel Computed Tomography Scan
Payabvash S, Khan AA, Qureshi MH, Saeed O, Suri MF, Qureshi AI. Detection of Intraparenchymal Hemorrhage After Endovascular Therapy in Patients with Acute Ischemic Stroke Using Immediate Postprocedural Flat‐Panel Computed Tomography Scan. Journal Of Neuroimaging 2015, 26: 213-218. PMID: 26282065, DOI: 10.1111/jon.12277.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrainBrain IschemiaFemaleHumansIntracranial HemorrhagesMaleMiddle AgedRetrospective StudiesStrokeThrombolytic TherapyTomography, X-Ray ComputedConceptsMultidetector CT studiesNegative predictive valueIschemic stroke patientsIntraparenchymal hemorrhageCT scanEndovascular treatmentHyperdense lesionParenchymal lesionsStroke patientsPredictive valueCT studiesMultidetector CTAcute ischemic stroke patientsAcute ischemic strokeAcute stroke patientsMultidetector CT scanPositive predictive valueEndovascular therapyIschemic strokePost procedureTomography scanSeparate cohortSuch lesionsPatientsDiagnostic valueAcute CT perfusion changes in seizure patients presenting to the emergency department with stroke-like symptoms: correlation with clinical and electroencephalography findings
Payabvash S, Oswood MC, Truwit CL, McKinney AM. Acute CT perfusion changes in seizure patients presenting to the emergency department with stroke-like symptoms: correlation with clinical and electroencephalography findings. Clinical Radiology 2015, 70: 1136-1143. PMID: 26155937, DOI: 10.1016/j.crad.2015.06.078.Peer-Reviewed Original ResearchMeSH KeywordsAgedBrainCerebrovascular CirculationElectroencephalographyEmergency Service, HospitalFemaleHumansMaleMiddle AgedRetrospective StudiesSeizuresTomography, X-Ray ComputedConceptsRelative cerebral blood flowRelative mean transit timeStroke-like symptomsSeizure patientsPerfusion changesClinical presentationEmergency departmentCTP examinationAcute stroke-like presentationAcute stroke-like symptomsNon-focal neurological deficitsSpeech deficitsStroke-like presentationSubset of patientsDifferent clinical presentationsCerebral blood flowEloquent brain regionsAdmission CTPElectroencephalography findingsNeurological deficitsSymptom onsetSuch patientsEarly followEEG findingsUnilateral motorMiddle Cerebral Artery Residual Contrast Stagnation on Noncontrast CT Scan Following Endovascular Treatment in Acute Ischemic Stroke Patients
Payabvash S, Qureshi MH, Taleb S, Pawar S, Qureshi AI. Middle Cerebral Artery Residual Contrast Stagnation on Noncontrast CT Scan Following Endovascular Treatment in Acute Ischemic Stroke Patients. Journal Of Neuroimaging 2015, 25: 946-951. PMID: 25684437, DOI: 10.1111/jon.12211.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke patientsMCA M1 occlusionIschemic stroke patientsIntraparenchymal hemorrhageEndovascular treatmentContrast stagnationCT scanPostprocedural CT scanNoncontrast CT scanStroke patientsM1 occlusionContralateral arteryHounsfield unitsAverage HU valueM1 segmentRelative riskNoncontrast CTPatientsScansArteryTreatmentAttenuation differenceHU valuesOcclusionRiskComparison of CT perfusion summary maps to early diffusion-weighted images in suspected acute middle cerebral artery stroke
Benson J, Payabvash S, Salazar P, Jagadeesan B, Palmer CS, Truwit CL, McKinney AM. Comparison of CT perfusion summary maps to early diffusion-weighted images in suspected acute middle cerebral artery stroke. European Journal Of Radiology 2015, 84: 682-689. PMID: 25623829, DOI: 10.1016/j.ejrad.2014.12.026.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreASPECTS scoreAcute middle cerebral artery strokeMiddle cerebral artery strokeAge-matched patientsDWI infarct volumeDiffusion-weighted imagingInfarct volumePositive patientsSymptom onsetArtery strokeCT scoreDiffusion-weighted imagesInfarct coreCTP examinationDWI volumePatientsDWIInfarctsScores
2014
Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment
Payabvash S, Qureshi MH, Khan SM, Khan M, Majidi S, Pawar S, Qureshi AI. Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment. Neuroradiology 2014, 56: 737-744. PMID: 24925217, DOI: 10.1007/s00234-014-1381-8.Peer-Reviewed Original ResearchConceptsPost-procedural CT scanAcute ischemic stroke patientsIschemic stroke patientsContrast extravasationIntraparenchymal hemorrhageEndovascular treatmentStroke patientsCT scanNoncontrast CT scanHyperdense lesionHounsfield unitsParenchymal lesionsImaging recordsIntroductionThis studyHemorrhagePatientsExtravasationLesionsScansHyperdensityHyperdenseTreatmentAverage attenuationCharacteristic analysisResultsOf
2013
Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients
Qian J, Payabvash S, Kemmling A, Lev MH, Schwamm LH, Betensky RA. Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients. Biometrics 2013, 70: 153-163. PMID: 24320930, PMCID: PMC3954429, DOI: 10.1111/biom.12113.Peer-Reviewed Original ResearchConceptsMassachusetts General HospitalCase-control studyStroke patientsAcute ischemic stroke patientsBrain regionsMatched Case-Control StudyHospital-Acquired PneumoniaIschemic stroke patientsLarge prospective studiesUnconditional logistic regressionCase-control designSpecific brain regionsAcquired PneumoniaAcute infarctionClinical featuresProspective studyClinical variablesGeneral HospitalEpidemiologic studiesPatientsModern imagingLarger studyLogistic regressionAppropriate statistical analysisHAP studiesScreening and detection of blunt vertebral artery injury in patients with upper cervical fractures: The role of cervical CT and CT angiography
Payabvash S, McKinney AM, McKinney ZJ, Palmer CS, Truwit CL. Screening and detection of blunt vertebral artery injury in patients with upper cervical fractures: The role of cervical CT and CT angiography. European Journal Of Radiology 2013, 83: 571-577. PMID: 24355656, DOI: 10.1016/j.ejrad.2013.11.020.Peer-Reviewed Original ResearchConceptsBlunt vertebral artery injuryVertebral artery injuryUpper cervical fracturesCervical fracturesSymptomatic strokeArtery injuryTrauma patientsBlunt trauma patientsPosterior circulation strokeScreening criteriaStrong interobserver agreementCervical CTCervical CTAUnderwent CTAClinical recordsNegative CTATransverse foramenCT angiographyCTA studiesClinical utilityPatientsInterobserver agreementC3-C7StrokeNECTGood Outcome Rate of 35% in IV-tPA–Treated Patients With Computed Tomography Angiography Confirmed Severe Anterior Circulation Occlusive Stroke
González RG, Furie KL, Goldmacher GV, Smith WS, Kamalian S, Payabvash S, Harris GJ, Halpern EF, Koroshetz WJ, Camargo EC, Dillon WP, Lev MH. Good Outcome Rate of 35% in IV-tPA–Treated Patients With Computed Tomography Angiography Confirmed Severe Anterior Circulation Occlusive Stroke. Stroke 2013, 44: 3109-3113. PMID: 24003051, PMCID: PMC4374554, DOI: 10.1161/strokeaha.113.001938.Peer-Reviewed Original ResearchConceptsAnterior circulation occlusionGood outcome rateIV-tPACT angiographyBetter outcomesRankin ScaleOutcome ratesAnterior circulation ischemic strokeHealth Stroke Scale scoreIntravenous tissue plasminogen activatorAdmission National InstitutesEndovascular therapy trialsNoncontrast CT scanningStroke Scale scoreLarge artery occlusionIV-tPA treatmentLogistic regression analysisTissue plasminogen activatorRoutine clinical protocolsSymptomatic strokeOcclusive strokeAcute strokeAdmission NIHSSArtery occlusionIschemic stroke