2007
Antioxidant administration with the initiation of fever prevents renal scarring in the rat model of acute pyelonephritis
Sadeghi Z, Kajbafzadeh A, Tajik P, Monajemzadeh M, Elmi A, Payabvash S, Salmasi A. Antioxidant administration with the initiation of fever prevents renal scarring in the rat model of acute pyelonephritis. Journal Of Pediatric Urology 2007, 3: s47. DOI: 10.1016/j.jpurol.2007.01.074.Peer-Reviewed Original ResearchAcute pyelonephritisCell apoptosis indexGroup 2Group 1Vitamin EAntioxidant administrationApoptosis indexEffectiveness of allopurinolTotal scar scoreMale Wister ratsSubsequent scar formationSeverity of scarringAntioxidant agentsBody temperatureDetection of feverRenal scaringRenal scarringRenal damageRenal scarsRight kidneyRat modelScar scoreProtective effectWister ratsAnimal models
2005
Paradoxical dose- and time-dependent regulation of superoxide dismutase and antioxidant capacity by vitamin E in rat
Golestani A, Rastegar R, Shariftabrizi A, Khaghani S, Payabvash SM, Salmasi AH, Dehpour AR, Pasalar P. Paradoxical dose- and time-dependent regulation of superoxide dismutase and antioxidant capacity by vitamin E in rat. Clinica Chimica Acta 2005, 365: 153-159. PMID: 16183047, DOI: 10.1016/j.cca.2005.08.008.Peer-Reviewed Original ResearchConceptsDosing groupVitamin ESOD activityAntioxidant capacitySignificant decreaseErythrocyte SOD activityPlasma antioxidant capacityVitamin E/Significant increaseEndogenous antioxidant systemNon-toxic dosesDose-dependent mannerTotal antioxidant capacitySerum levelsSame dosesBody weightNontoxic dosesWeeksControl levelsTime-dependent regulationAntioxidant defenseDosesSuperoxide dismutaseRatsAntioxidant system