2007
Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion
Payabvash S, Salmasi AH, Kiumehr S, Tavangar SM, Nourbakhsh B, Faghihi SH, Dehpour AR. Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion. Urologia Internationalis 2007, 79: 248-254. PMID: 17940358, DOI: 10.1159/000107958.Peer-Reviewed Original ResearchConceptsAdministration of NACGerm cell apoptosis indicesIschemia/reperfusion injuryTorsion/detorsionCell apoptosis indexRat modelN-acetylcysteineApoptosis indexReperfusion injuryTesticular torsionProtective effectGroup 2Control groupTesticular torsion/detorsionNAC 30 minRenal tissue damageSprague-Dawley ratsGroup 1 animalsGerm cell apoptosisIntraperitoneal injectionSham operationSaline injectionSystemic administrationTherapeutic doseAntioxidant balance
2005
Effect of morphine on ischemia-reperfusion injury: Experimental study in testicular torsion rat model
Salmasi AH, Beheshtian A, Payabvash S, Demehri S, Ebrahimkhani MR, Karimzadegan M, Bahadori M, Pasalar P, Dehpour AR. Effect of morphine on ischemia-reperfusion injury: Experimental study in testicular torsion rat model. Urology 2005, 66: 1338-1342. PMID: 16360480, DOI: 10.1016/j.urology.2005.06.101.Peer-Reviewed Original ResearchConceptsMorphine groupEffects of morphineTesticular torsionD groupMorphine sulfateBaseline groupMalondialdehyde levelsRight testis 720 degreesAdult male Sprague-DawleyBasal normal valuesHours of detorsionIntravenous morphine sulfateIschemia-reperfusion injurySham-operated groupTesticular malondialdehyde levelsUnilateral testicular torsionMale Sprague-DawleySimilar histopathologic changesNaltrexone groupReperfusion injuryReperfusion phaseHistopathologic changesOpioid receptorsTesticular ischemiaIpsilateral testis