2008
Administration of N-Acetylcysteine Reduces Germ Cell-Specific Apoptosis and Oxidative Injury Following Testicular Torsion in Rats
Payabvash S, Kiumehr S, Salmasi A, Tavangar S, Dehpour A. Administration of N-Acetylcysteine Reduces Germ Cell-Specific Apoptosis and Oxidative Injury Following Testicular Torsion in Rats. Journal Of Pediatric Urology 2008, 4: s29. DOI: 10.1016/j.jpurol.2008.01.059.Peer-Reviewed Original ResearchGerm cell apoptosis indicesAdministration of NACCell apoptosis indexN-acetylcysteineGroup 2Tissue damageTesticular torsionRat modelAntioxidant balanceProtective effectGroup 1 underwent sham operationsControl groupDose of NACApoptosis indexIschemia/reperfusion syndromeGerm cell-specific apoptosisAbdominal aortic aneurysmectomyTorsion/detorsionRenal tissue damageUnderwent sham operationAnti-inflammatory propertiesIschemia/reperfusionMethodsSprague–Dawley ratsGerm cell apoptosisAortic aneurysmectomy
2007
Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion
Payabvash S, Salmasi AH, Kiumehr S, Tavangar SM, Nourbakhsh B, Faghihi SH, Dehpour AR. Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion. Urologia Internationalis 2007, 79: 248-254. PMID: 17940358, DOI: 10.1159/000107958.Peer-Reviewed Original ResearchConceptsAdministration of NACGerm cell apoptosis indicesIschemia/reperfusion injuryTorsion/detorsionCell apoptosis indexRat modelN-acetylcysteineApoptosis indexReperfusion injuryTesticular torsionProtective effectGroup 2Control groupTesticular torsion/detorsionNAC 30 minRenal tissue damageSprague-Dawley ratsGroup 1 animalsGerm cell apoptosisIntraperitoneal injectionSham operationSaline injectionSystemic administrationTherapeutic doseAntioxidant balanceAntioxidant administration with the initiation of fever prevents renal scarring in the rat model of acute pyelonephritis
Sadeghi Z, Kajbafzadeh A, Tajik P, Monajemzadeh M, Elmi A, Payabvash S, Salmasi A. Antioxidant administration with the initiation of fever prevents renal scarring in the rat model of acute pyelonephritis. Journal Of Pediatric Urology 2007, 3: s47. DOI: 10.1016/j.jpurol.2007.01.074.Peer-Reviewed Original ResearchAcute pyelonephritisCell apoptosis indexGroup 2Group 1Vitamin EAntioxidant administrationApoptosis indexEffectiveness of allopurinolTotal scar scoreMale Wister ratsSubsequent scar formationSeverity of scarringAntioxidant agentsBody temperatureDetection of feverRenal scaringRenal scarringRenal damageRenal scarsRight kidneyRat modelScar scoreProtective effectWister ratsAnimal modelsEndogenous opioids modulate hepatocyte apoptosis in a rat model of chronic cholestasis: the role of oxidative stress
Payabvash S, Kiumehr S, Nezami BG, Zandieh A, Anvari P, Tavangar SM, Dehpour AR. Endogenous opioids modulate hepatocyte apoptosis in a rat model of chronic cholestasis: the role of oxidative stress. Liver International 2007, 27: 538-547. PMID: 17403194, DOI: 10.1111/j.1478-3231.2007.01457.x.Peer-Reviewed Original ResearchConceptsAnti-oxidant balanceBile duct ligationChronic cholestasisEndogenous opioidsCholestatic ratsHepatocyte apoptosisOpioid antagonistRat modelHepatic lipid peroxidation levelsSerum liver enzymesCholestatic liver diseaseEndogenous opioid systemHepatic glutathione levelsAnti-oxidant defensesLipid peroxidation levelsAnti-oxidant enzyme activitiesChronic treatmentNaltrexone treatmentCholestatic animalsLiver diseaseBDL ratsHepatic damageDuct ligationLiver enzymesCholestasis