2008
Ethyl pyruvate reduces germ cell–specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion
Payabvash S, Kiumehr S, Tavangar SM, Dehpour AR. Ethyl pyruvate reduces germ cell–specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion. Journal Of Pediatric Surgery 2008, 43: 705-712. PMID: 18405719, DOI: 10.1016/j.jpedsurg.2007.12.063.Peer-Reviewed Original ResearchConceptsEthyl pyruvate solutionRinger's ethyl pyruvate solutionProtective effectRight testisTissue damageMPO activityTesticular torsionGroup 2Sperm countGerm cell apoptosis indicesLong-term testicular functionTesticular torsion/detorsionGerm cell-specific apoptosisLipid peroxidationApoptotic tissue damageTestis tissue damageTorsion/detorsionGroup 2 ratsAnti-inflammatory propertiesSprague-Dawley ratsGroup 24 hoursEpididymal sperm concentrationEthyl pyruvateCell apoptosis indexPyruvate solutionAdministration of N-Acetylcysteine Reduces Germ Cell-Specific Apoptosis and Oxidative Injury Following Testicular Torsion in Rats
Payabvash S, Kiumehr S, Salmasi A, Tavangar S, Dehpour A. Administration of N-Acetylcysteine Reduces Germ Cell-Specific Apoptosis and Oxidative Injury Following Testicular Torsion in Rats. Journal Of Pediatric Urology 2008, 4: s29. DOI: 10.1016/j.jpurol.2008.01.059.Peer-Reviewed Original ResearchGerm cell apoptosis indicesAdministration of NACCell apoptosis indexN-acetylcysteineGroup 2Tissue damageTesticular torsionRat modelAntioxidant balanceProtective effectGroup 1 underwent sham operationsControl groupDose of NACApoptosis indexIschemia/reperfusion syndromeGerm cell-specific apoptosisAbdominal aortic aneurysmectomyTorsion/detorsionRenal tissue damageUnderwent sham operationAnti-inflammatory propertiesIschemia/reperfusionMethodsSprague–Dawley ratsGerm cell apoptosisAortic aneurysmectomy
2007
Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion
Payabvash S, Salmasi AH, Kiumehr S, Tavangar SM, Nourbakhsh B, Faghihi SH, Dehpour AR. Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion. Urologia Internationalis 2007, 79: 248-254. PMID: 17940358, DOI: 10.1159/000107958.Peer-Reviewed Original ResearchConceptsAdministration of NACGerm cell apoptosis indicesIschemia/reperfusion injuryTorsion/detorsionCell apoptosis indexRat modelN-acetylcysteineApoptosis indexReperfusion injuryTesticular torsionProtective effectGroup 2Control groupTesticular torsion/detorsionNAC 30 minRenal tissue damageSprague-Dawley ratsGroup 1 animalsGerm cell apoptosisIntraperitoneal injectionSham operationSaline injectionSystemic administrationTherapeutic doseAntioxidant balanceAntioxidant administration with the initiation of fever prevents renal scarring in the rat model of acute pyelonephritis
Sadeghi Z, Kajbafzadeh A, Tajik P, Monajemzadeh M, Elmi A, Payabvash S, Salmasi A. Antioxidant administration with the initiation of fever prevents renal scarring in the rat model of acute pyelonephritis. Journal Of Pediatric Urology 2007, 3: s47. DOI: 10.1016/j.jpurol.2007.01.074.Peer-Reviewed Original ResearchAcute pyelonephritisCell apoptosis indexGroup 2Group 1Vitamin EAntioxidant administrationApoptosis indexEffectiveness of allopurinolTotal scar scoreMale Wister ratsSubsequent scar formationSeverity of scarringAntioxidant agentsBody temperatureDetection of feverRenal scaringRenal scarringRenal damageRenal scarsRight kidneyRat modelScar scoreProtective effectWister ratsAnimal models