2008
Ethyl pyruvate reduces germ cell–specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion
Payabvash S, Kiumehr S, Tavangar SM, Dehpour AR. Ethyl pyruvate reduces germ cell–specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion. Journal Of Pediatric Surgery 2008, 43: 705-712. PMID: 18405719, DOI: 10.1016/j.jpedsurg.2007.12.063.Peer-Reviewed Original ResearchConceptsEthyl pyruvate solutionRinger's ethyl pyruvate solutionProtective effectRight testisTissue damageMPO activityTesticular torsionGroup 2Sperm countGerm cell apoptosis indicesLong-term testicular functionTesticular torsion/detorsionGerm cell-specific apoptosisLipid peroxidationApoptotic tissue damageTestis tissue damageTorsion/detorsionGroup 2 ratsAnti-inflammatory propertiesSprague-Dawley ratsGroup 24 hoursEpididymal sperm concentrationEthyl pyruvateCell apoptosis indexPyruvate solutionAdministration of N-Acetylcysteine Reduces Germ Cell-Specific Apoptosis and Oxidative Injury Following Testicular Torsion in Rats
Payabvash S, Kiumehr S, Salmasi A, Tavangar S, Dehpour A. Administration of N-Acetylcysteine Reduces Germ Cell-Specific Apoptosis and Oxidative Injury Following Testicular Torsion in Rats. Journal Of Pediatric Urology 2008, 4: s29. DOI: 10.1016/j.jpurol.2008.01.059.Peer-Reviewed Original ResearchGerm cell apoptosis indicesAdministration of NACCell apoptosis indexN-acetylcysteineGroup 2Tissue damageTesticular torsionRat modelAntioxidant balanceProtective effectGroup 1 underwent sham operationsControl groupDose of NACApoptosis indexIschemia/reperfusion syndromeGerm cell-specific apoptosisAbdominal aortic aneurysmectomyTorsion/detorsionRenal tissue damageUnderwent sham operationAnti-inflammatory propertiesIschemia/reperfusionMethodsSprague–Dawley ratsGerm cell apoptosisAortic aneurysmectomy
2007
Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion
Payabvash S, Salmasi AH, Kiumehr S, Tavangar SM, Nourbakhsh B, Faghihi SH, Dehpour AR. Salutary Effects of N-Acetylcysteine on Apoptotic Damage in a Rat Model of Testicular Torsion. Urologia Internationalis 2007, 79: 248-254. PMID: 17940358, DOI: 10.1159/000107958.Peer-Reviewed Original ResearchConceptsAdministration of NACGerm cell apoptosis indicesIschemia/reperfusion injuryTorsion/detorsionCell apoptosis indexRat modelN-acetylcysteineApoptosis indexReperfusion injuryTesticular torsionProtective effectGroup 2Control groupTesticular torsion/detorsionNAC 30 minRenal tissue damageSprague-Dawley ratsGroup 1 animalsGerm cell apoptosisIntraperitoneal injectionSham operationSaline injectionSystemic administrationTherapeutic doseAntioxidant balance