2024
Brain Care Score and Neuroimaging Markers of Brain Health in Asymptomatic Middle-Age Persons
Rivier C, Singh S, Senff J, Tack R, Marini S, Clocchiatti-Tuozzo S, Huo S, Renedo D, Papier K, Conroy M, Littlejohns T, Chemali Z, Kourkoulis C, Payabvash S, Newhouse A, Westover M, Lazar R, Pikula A, Ibrahim S, Howard V, Howard G, Brouwers H, Van Duijn C, Fricchione G, Tanzi R, Yechoor N, Sheth K, Anderson C, Rosand J, Falcone G. Brain Care Score and Neuroimaging Markers of Brain Health in Asymptomatic Middle-Age Persons. Neurology 2024, 103: e209687. PMID: 39052961, DOI: 10.1212/wnl.0000000000209687.Peer-Reviewed Original ResearchConceptsCare scoresUK BiobankWhite matter hyperintensitiesHealth-related behaviorsMarkers of brain healthMiddle-aged personsStroke risk factorsProspective cohort studyMultivariate linear regressionEmpower patientsSilent cerebrovascular diseaseBrain careWhite matter hyperintensities progressionDementia historyHealth declineInvestigate associationsCohort studyBrain healthNeuroimaging markersHigher scoresRisk factorsMean diffusivityCerebrovascular diseaseFractional anisotropyImaging assessment
2023
Association of Poor Oral Health With Neuroimaging Markers of White Matter Injury in Middle-Aged Participants in the UK Biobank.
Rivier C, Renedo D, de Havenon A, Sunmonu N, Gill T, Payabvash S, Sheth K, Falcone G. Association of Poor Oral Health With Neuroimaging Markers of White Matter Injury in Middle-Aged Participants in the UK Biobank. Neurology 2023, 102: e208010. PMID: 38165331, PMCID: PMC10870735, DOI: 10.1212/wnl.0000000000208010.Peer-Reviewed Original ResearchConceptsPoor oral healthOral healthBrain healthRisk factorsNeuroimaging markerWMH volumeHealth profileMD scoreSelf-reported poor oral healthCross-sectional neuroimaging studiesFractional anisotropyWhite matter hyperintensity volumeModifiable risk factorsWhite matter injuryPresence of denturesMendelian randomizationMiddle-aged personsFA scoreMiddle-aged participantsLoose teethCardiovascular diseaseHyperintensity volumeBrain MRIModifiable processEarly interventionPopulation level multimodal neuroimaging correlates of attention-deficit hyperactivity disorder among children
Lin H, Haider S, Kaltenhauser S, Mozayan A, Malhotra A, Constable R, Scheinost D, Ment L, Konrad K, Payabvash S. Population level multimodal neuroimaging correlates of attention-deficit hyperactivity disorder among children. Frontiers In Neuroscience 2023, 17: 1138670. PMID: 36908780, PMCID: PMC9992191, DOI: 10.3389/fnins.2023.1138670.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderADHD diagnosisHyperactivity disorderChildhood attention deficit hyperactivity disorderAssociation of ADHDDorsal attention networkFunctional MRI studyDefault mode networkResting-state fMRIADHD childrenAttention functionLimitations of machineAttention networkFrontal regionsNeuroimaging datasetsNeurobiological implicationsParietal lobeFrontal lobe cortexCortical volumeFractional anisotropyFunctional neuroimaging datasetsChildrenWhite matter tractsNeurite densityMicrostructural integrity