Nitric oxide modulates glutathione synthesis during endotoxemia
Payabvash S, Ghahremani MH, Goliaei A, Mandegary A, Shafaroodi H, Amanlou M, Dehpour AR. Nitric oxide modulates glutathione synthesis during endotoxemia. Free Radical Biology And Medicine 2006, 41: 1817-1828. PMID: 17157184, DOI: 10.1016/j.freeradbiomed.2006.09.010.Peer-Reviewed Original ResearchConceptsNitric oxide synthesisOxide synthesisHepatic glutathione synthesisGlutathione levelsGlutathione synthesisInjection of lipopolysaccharideHepatic glutathione concentrationHepatic glutathione levelsEndotoxin-induced changesNitric oxide formationIntracellular glutathione levelsEndotoxemic miceLiver glutathioneEndotoxemiaNitric oxideGlutathione peroxidaseGlutathione fluxOxidative stressGlutathione concentrationGlutathione statusAntioxidant defenseGlutathione S-transferaseCysteine precursorLipopolysaccharideGlutathione metabolism