Admission CT Perfusion Is an Independent Predictor of Hemorrhagic Transformation in Acute Stroke with Similar Accuracy to DWI
Souza LC, Payabvash S, Wang Y, Kamalian S, Schaefer P, Gonzalez RG, Furie KL, Lev MH. Admission CT Perfusion Is an Independent Predictor of Hemorrhagic Transformation in Acute Stroke with Similar Accuracy to DWI. Cerebrovascular Diseases 2011, 33: 8-15. PMID: 22143195, PMCID: PMC3250646, DOI: 10.1159/000331914.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBostonCerebrovascular CirculationChi-Square DistributionDiffusion Magnetic Resonance ImagingFemaleHumansIntracranial HemorrhagesLogistic ModelsMaleMiddle AgedMultivariate AnalysisPatient AdmissionPerfusion ImagingPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC CurveStrokeTomography, X-Ray ComputedConceptsRelative mean transit timeAdmission CT perfusionDiffusion-weighted imagingPredictors of HTRelative cerebral blood flowHemorrhagic transformationCT perfusionAcute strokeIndependent predictorsTissue volumeAdmission diffusion-weighted imagingConsecutive stroke patientsOnly independent predictorCerebral blood flowIschemic hemisphereMechanical thrombectomyStroke patientsInfarct coreMean transit timeBlood flowTest characteristicsCurve analysisDWI scansLesionsStrokeCT Cerebral Blood Flow Maps Optimally Correlate With Admission Diffusion-Weighted Imaging in Acute Stroke but Thresholds Vary by Postprocessing Platform
Kamalian S, Kamalian S, Maas MB, Goldmacher GV, Payabvash S, Akbar A, Schaefer PW, Furie KL, Gonzalez RG, Lev MH. CT Cerebral Blood Flow Maps Optimally Correlate With Admission Diffusion-Weighted Imaging in Acute Stroke but Thresholds Vary by Postprocessing Platform. Stroke 2011, 42: 1923-1928. PMID: 21546490, PMCID: PMC3125441, DOI: 10.1161/strokeaha.110.610618.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingCT perfusion parametersAcute strokeCT perfusionInfarct coreAdmission diffusion-weighted imagingPerfusion parametersCerebral blood flowCerebral blood flow mapsCerebral blood volumeCharacteristic curve analysisAdmission CT perfusionBlood flow mapsUninvolved hemisphereRegional Ischemic Vulnerability of the Brain to Hypoperfusion
Payabvash S, Souza LC, Wang Y, Schaefer PW, Furie KL, Halpern EF, Gonzalez RG, Lev MH. Regional Ischemic Vulnerability of the Brain to Hypoperfusion. Stroke 2011, 42: 1255-1260. PMID: 21493917, PMCID: PMC3090217, DOI: 10.1161/strokeaha.110.600940.Peer-Reviewed Original ResearchConceptsIschemic vulnerabilityStroke patientsInfarct coreRCBF thresholdAdmission diffusion-weighted imagingCerebral blood flow reductionAcute stroke patientsIschemic stroke onsetBlood flow reductionAdmission CT perfusionDiffusion-weighted imagingCT perfusion mapsStroke onsetRCBF reductionCT perfusionBrain lesionsInferior frontal gyrusParacentral lobuleCaudate bodyInsular ribbonPerfusion parameter mapsHypoperfusionSubcortical regionsPatientsRCBF