Posttraumatic Stress Disorder, Antidepressant Use, and Hemorrhagic Stroke in Young Men and Women
Gaffey AE, Rosman L, Burg MM, Haskell SG, Brandt CA, Skanderson M, Dziura J, Sico JJ. Posttraumatic Stress Disorder, Antidepressant Use, and Hemorrhagic Stroke in Young Men and Women. Stroke 2020, 52: 121-129. PMID: 33297868, PMCID: PMC7770089, DOI: 10.1161/strokeaha.120.030379.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderHemorrhagic strokeHealth care utilizationUse of SSRIsGreater riskSSRI useStroke riskCare utilizationStress disorderEffects of PTSDIncident hemorrhagic strokeMiddle-aged veteransModifiable risk factorsNon-pharmacological treatmentMultivariate Cox modelNorepinephrine reuptake inhibitorsOverall incidence rateHemorrhagic stroke riskSNRI useIncident strokeAntidepressant useReuptake inhibitorsComorbid conditionsLifestyle factorsPsychiatric comorbidityAssociations between obstructive sleep apnea and prescribed opioids among veterans.
Chen K, Yaggi HK, Fiellin DA, DeRycke EC, Athar W, Haskell S, Bastian LA. Associations between obstructive sleep apnea and prescribed opioids among veterans. Pain 2020, 161: 2035-2040. PMID: 32358418, PMCID: PMC7606219, DOI: 10.1097/j.pain.0000000000001906.Peer-Reviewed Original ResearchConceptsDiagnosis of OSAObstructive sleep apneaOpioid prescriptionsRelative risk ratiosSleep apneaMultimodal pain management strategiesPoor pain controlTwo-fold likelihoodPain management strategiesHigher pain intensityPain controlPrescribed opioidsFormer smokersPain intensityPain managementPrimary outcomeChronic prescriptionPrescription opioidsPsychiatric comorbidityOSA treatmentPrimary exposureNational cohortRisk ratioChronic durationOpioid category