Associations between obstructive sleep apnea and prescribed opioids among veterans.
Chen K, Yaggi HK, Fiellin DA, DeRycke EC, Athar W, Haskell S, Bastian LA. Associations between obstructive sleep apnea and prescribed opioids among veterans. Pain 2020, 161: 2035-2040. PMID: 32358418, PMCID: PMC7606219, DOI: 10.1097/j.pain.0000000000001906.Peer-Reviewed Original ResearchConceptsDiagnosis of OSAObstructive sleep apneaOpioid prescriptionsRelative risk ratiosSleep apneaMultimodal pain management strategiesPoor pain controlTwo-fold likelihoodPain management strategiesHigher pain intensityPain controlPrescribed opioidsFormer smokersPain intensityPain managementPrimary outcomeChronic prescriptionPrescription opioidsPsychiatric comorbidityOSA treatmentPrimary exposureNational cohortRisk ratioChronic durationOpioid categoryAssociation of prescription opioids and incident cardiovascular risk factors among post-9/11 Veterans
Chui PW, Gordon KS, Dziura J, Burg MM, Brandt CA, Sico JJ, Leapman MS, Cavanagh CE, Rosman L, Haskell S, Becker WC, Bastian LA. Association of prescription opioids and incident cardiovascular risk factors among post-9/11 Veterans. Preventive Medicine 2020, 134: 106036. PMID: 32097753, DOI: 10.1016/j.ypmed.2020.106036.Peer-Reviewed Original ResearchConceptsCVD risk factorsLong-term opioid therapyCurrent smoking statusRisk factorsOpioid useOpioid therapySmoking statusCardiovascular diseaseHigh riskLong-term exposureIncident cardiovascular risk factorsModifiable CVD risk factorsPrevalent CVD risk factorsFirst primary care visitCardiovascular risk factorsPrimary care visitsBaseline periodElectronic health record dataMain outcome measuresHealth record dataOpioid prescriptionsCare visitsPrescription opioidsMain exposureOutcome measures